Sökning: "Immunoassay"

Visar resultat 1 - 5 av 116 avhandlingar innehållade ordet Immunoassay.

1. 1. Membrane-Assisted Isoform ImmunoAssay : Separation and determination of protein isoforms

   Författare :Maria Lönnberg; Carl G M Magnusson; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; Bioteknik; Bioengineering; Bioteknik; Surface Biotechnology; ytbioteknik;

   Sammanfattning : Proteins exist in a variety of isoforms with minor differences, mostly due to their glycosylation patterns, which can modulate their biological functions. It seems to be of clinical relevance to measure the isoform-distribution.Thesis describes a novel technology named Membrane-Assisted Isoform ImmunoAssay (MAIIA). LÄS MER

3. 2. Avian antibodies applied in particle enhanced turbidimetric immunoassay : Developement of serum/plasma calprotectin immunoassay and its clinical performance as a marker for bacterial infections

   Författare :Tom Nilsen; Anders Larsson; Bjørn Steen Skålhegg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sepsis; avian antibodies; calprotectin antigen; particle enhanced turbidimetric immunoassay.; Clinical Chemistry; Klinisk kemi;

   Sammanfattning : Calprotectin is a cytosolic protein in the granulocytes, consisting of S100A8 and S100A9. On the site of inflammation, the neutrophils release the cytosol as an inflammatory response. The circulating calprotectin concentration increases and can therefore be used as marker for neutrophil activation and inflammation. LÄS MER

4. 3. Design and development of electrochemical sensors with application in bioanalysis

   Författare :Kinga Zor; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bioanalysis; electrochemistry; sensor; biosensor; miniaturization; real sample; immunoassay; μTAS;

   Sammanfattning : There is a continuous search for reliable, robust, easy to use, portable and cost effective analytical tools with applications in food industry, biomedicine, environmental monitoring and homeland security. The main focus of this thesis is the development of electrochemical (bio)sensors and bioanalysis systems (to be applied in two major fields of interest: food & beverage industry and biomedical research) for monitoring key analytes in complex matrices, such as: meat samples, fermentation broths, and cell culture media. LÄS MER

5. 4. Development and Application of Enzyme- and Antibody-based Assays with Emphasis on Selectivity, Sensitivity and Stability

   Författare :Catalin Nistor; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; stability; sensitivity; selectivity; cross-reactivity; sample matrix effects; environmental pollutants; enzyme biosensor; immunoassay; Analytical chemistry; Analytisk kemi;

   Sammanfattning : This thesis presents the development, optimisation, and various applications of enzyme-based biosensors and immunoassays, mainly with relevance to environmental analysis. the thesis discusses problems and possible solutions associated with selectivity, sensitivity and robustness of such bioassays with emphasis on various immunoasssay configurations for determination of surfactants, phenols, or drugs, and amperometric biosensors based on enzymes (e. LÄS MER

7. 5. Biomarker detection via lab-on-a-chip integrated immunoaffinity approach for fluorescence and mass spectrometry readout

   Författare :Asilah Ahmad Tajudin; Avdelningen för Biomedicinsk teknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; immunoaffinity; affinity prefractionation; immunoMALDI; solid-phase extraction; protein digestion; ISET; antibody microarray; signal amplification; fluorescence; microfluidics; lab on a chip; separation; acoustophoresis; ultrasound; acoustic radiation force; plasma; proteomics; MALDI mass spectrometry; immunoassay; porous silicon.;

   Sammanfattning : The blood/plasma protein biomarker profile represents the pathological and physiological changes relating to human diseases. However, the plasma proteome reflects a high degree of complexity that results in a challenge for most analytical methods in clinical diagnostics. LÄS MER