Sökning: "Immunoadsorption"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet Immunoadsorption.

1. 1. Extracorporeal immunoadsorption

   Författare :Christian Freiburghaus; Avdelningen för klinisk kemi och farmakologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Klinisk kemi; Clinical chemistry; tolerance induction; inhibitors; haemophilia; Extracorporeal immunoadsorption; antibody elimination; serology; transplantation; Immunologi; serologi;

   Sammanfattning : Antibodies are important protein structures in the immunological defence. Occasionally the regulation of the production of these antibodies fails and antibodies directed against self structures are produced in large scale. Antibody production can also complicate or make transfusions and transplantations impossible. LÄS MER

3. 2. Improving radioimmunotargeting of tumors : the impact of extracorporeal immunoadsorption and preload in rats

   Författare :Michael Garkavij; Bröstcancer-genetik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; preload.; immunoadsorption; MAb; rat; Tumor; radioimmunotargeting; oncology; cancerology; Cytologi; onkologi; cancer;

   Sammanfattning : In radioimmunotherapy of tumors, uptake of the monoclonal antibody (MAb) used is often too low in relation to its uptake in normal tissues. The purpose of these studies was to improve experimental tumor radioimmunotargeting with (a) extracorporeal immunoadsorption (ECIA), where excess of radiolabeled MAbs circulating in blood is removed, (b) or by preload with unlabeled MAb prior to injection of radiolabeled MAb, (c) or by a combination of these. LÄS MER

4. 3. Immunoglobulins, immunoglobulin subclass-distributions and serologic markers in some renal and systemic disorders

   Författare :Gabriel Almroth; Jan Björklander; Linköpings universitet; []
   Nyckelord :Immunoglobulins; immunoglobulin-subclass distribution; hydralazine; ANCA; anti-:MPO; primary SjOgren s syndrome; hepatitis B vaccination; anti-HBssubclasses; immunoadsorption; plasmapheresis; antibodies; hepatitis C virus; transmission; recombinant immunoblot assay; hepatitis C genotype; MEDICINE; MEDICIN;

   Sammanfattning : In this study we evaluated pathogenetic factors and possible mediators of renal and systemic disorders where immunologic mechanisms might be of importance.An abberant immunoglobulin and IgG-subclass distribution was detected in 103 patients with primary and secondary glomerulonephritis as well as in 38 patients with the systemic disease primary Sjögren 's syndrome or purpura hypergammaglobulinemica (elevated IgG1 and low IgG2 ). LÄS MER

5. 4. Pathophysiological importance of Beta1-Adrenergic receptor autoantibodies in the development of cardiomyopathy and heart failure. Clinically and experimentally

   Författare :Lisa Buvall; Göteborgs universitet; []
   Nyckelord :Dilated Cardiomyopathy; Beta1 Adrenergic Receptor; Antibody; Cardiac; Function; Intravenous Immunoglobulin; Immunoadsorption; Cultured Cardiomyocytes; ; rat; mice; GRK2;

   Sammanfattning : Idiopathic Dilated Cardiomyopathy (DCM) is a heart muscle disease of unknown originthat is characterized by ventricular dilation and the impaired contraction of the left orboth ventricles, resulting in progressive heart failure and sudden cardiac death. Antibodiesagainst different cardiac proteins have been found in DCM; they include antibodiesagainst the �1-adrenergic receptor (�1AR). LÄS MER

7. 5. AB0-incompatible kidney transplantation using antigen-specific immunoadsorption and rituximab

   Författare :Helena Genberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : 5As the demand for kidney transplantation is constantly growing methods to expand the donor pool have become increasingly important. AB0-incompatibility has hitherto been regarded as an absolute contraindication to living donor donation. LÄS MER