Sökning: "Immune inhibitory receptor"

Visar resultat 16 - 20 av 111 avhandlingar innehållade orden Immune inhibitory receptor.

  1. 16. NK cell and dendritic cell interactions in innate immune responses

    Författare :Catrine M Persson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; Dendritic cells; crosstalk; recruitment; activation; CD94 NKG2AQa1; Toxoplasma gondii;

    Sammanfattning : Natural killer (NK) cells are cytotoxic cells of the innate immune system. They have been found to be critical in the defense against infections and also against some tumors. Recent studies have shown that NK cells require signals from accessory cells to induce their recruitment and activation at the site of infection or tumor growth. LÄS MER

  3. 17. Fc receptors and feedback enhancement of antibody responses

    Författare :Sara Wernersson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; mouse; transgenic knockout; immune regulation; B lymphocytes; Fc receptors; IgG; IgE; FcgRI; FcgRII; FcgRIII; CD23; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Antibodies are important for the defence against microorganisms, but are also involved inpathological reactions such as allergy or autoimmunity. The exact mechanisms involved inregulation of antibody responses is still largely unknown. In this thesis, immune regulationby antibodies and the receptors they bind to (FcR), were investigated. LÄS MER

  4. 18. NK cell recognition of herpesviruses : mechanisms of viral immune escape

    Författare :Alexander Rölle; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Herpesviruses are ubiquitous pathogens which after an often asymptomatic infection establish lifelong latency in the host. Control of the viral infection depends on both innate and adaptive immune system. LÄS MER

  5. 19. HIV-induced humoral immune response with specific relevance to IgA

    Författare :Pia Skott; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; secretory lgA; neutralizing antibodies; mucosal immunity;

    Sammanfattning : Human Immunodeficiency Virus (HIV) transmission occurs primarily after hetero- and homosexual contact and across mucosal surfaces. The immune response in mucosal tissues is typified by secretory immunoglobulin A (SIgA), which is the predominant lg class in human external secretions. LÄS MER

  7. 20. Decoding NK cell receptor specificity : functional and structural studies of MHC class 1 subcomponents

    Författare :Jakob Michaëlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; MHC class 1; inhibitory receptors;

    Sammanfattning : Natural Killer (NK) cells are an important part of the innate immune system. They can lyse target cells and secrete immunoregulatory cytokines early during immune responses. They mediate protection against viruses and tumours, and can reject MHC class I mismatched bone marrow grafts. LÄS MER