Sökning: "Immune infiltrates"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden Immune infiltrates.

  1. 1. Mutation and immune profiling of non-small cell lung cancer

    Författare :Linnéa La Fleur; Johan Botling; Fernando López-Ríos; Uppsala universitet; []
    Nyckelord :Non-small cell lung cancer; Tumor microenvironment; Tumor-associated macrophages; Immune infiltrates; PD-L1; Mutation patterns; Immune therapy; MARCO; TP53; STK11; KRAS;

    Sammanfattning : Several novel therapies that target molecular alterations and immune checkpoints in lung cancer have been introduced in the last decade. Still, only a minority of patients obtain long term disease control and overall survival remains poor. LÄS MER

  3. 2. Cellular immune responses to low density lipoprotein in atherosclerosis

    Författare :Andreas Hermansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is an inflammatory disease of the medium and large sized arterial vessels. Low density lipoprotein (LDL) particles carrying cholesterol are trapped within the arterial intima and elicit both innate as well as adaptive immune responses. LÄS MER

  4. 3. Mapping the immune landscape in solid tumors : implications for immunotherapy

    Författare :Emelie Foord; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Our cells are programmed with various safety mechanisms to avoid transformation into tumor cells. In case these fail, we have a guarding immune system ready to recognize and eliminate these cells. Despite these safety measurements, cancer is one of the leading causes of death worldwide. The tumor cells find ways to escape the immune system. LÄS MER

  5. 4. Role of tubular scattered cells of the kidney in disease and regeneration

    Författare :Krzysztof Krawczyk; Malmö Klinisk patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney Diseases; acute kidney disease; acute kidney injury; chronic kidney disease; SOX9; pIgR; Polymeric immunoglobulin receptor; Immune cells; papillary carcinoma; pRCC; Kidney cancer;

    Sammanfattning : With well over 700 000 deaths every year worldwide, kidney disease constitutes an immense health problem for patients and society. The total global number of people with kidney disease regardless of severity amounts to a staggering 600 000 000. LÄS MER

  7. 5. Studies on Oral Immune Reactions in the Genetically Mercury-Sensitive BN Rat and in the Hyperplastic BN-(BNxLEW) Graft-versus-Host Disease

    Författare :Michael J Peszkowski; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T-lymphocytes; Immunohistochemistry; autoimmunity; stomatology; Odontology; Odontologi;

    Sammanfattning : Mercury (Hg) is known to induce adverse immune reactions in sensitive individuals. e.g. selected inbred animal strains. LÄS MER