Sökning: "Ileum"

Visar resultat 1 - 5 av 52 avhandlingar innehållade ordet Ileum.

1. 1. Structure, evolution and expression of glandular kallikrein genes

   Författare :Yvonne Ceder; Malmö Klinisk kemi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ileum.; Clinical chemistry; Klinisk kemi; Tissue distribution; Androgen responsive element; Ortholog; Evolution; Prostate cancer; Glandular kallikreins; Prostate-specific antigen;

   Sammanfattning : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. LÄS MER

3. 2. Mucosal dendritic cells in inflammatory bowel disease

   Författare :Sa'ad Yislam Salim; Johan D. Söderholm; Mary jo Wick; Linköpings universitet; []
   Nyckelord :Blood; Crohn s disease; dendritic cells; E. coli; FACS; follicle-associated; epithelium; human; ileum; mixed lymphocyte reaction; permeability; Peyer s patches; SAMP1 YitFc; Ussing chambers; villous epithelium; MEDICINE; MEDICIN;

   Sammanfattning : Crohn's disease, a chronic inflammation of the bowel, is a multi-factorial condition where uncontrolled immune responses to luminal bacteria occur in genetically predisposed individuals. The first observable clinical signs are small ulcers that form at a specialised form of epithelium, follicle-associated epithelium (FAB). LÄS MER

4. 3. Epithelial barrier dysfunction in ileal Crohn's disease

   Författare :Johan Dabrosin-Söderholm; Svante Nordgren; Linköpings universitet; []
   Nyckelord :acetylsalicylic add; confocal microscopy; Crohn s disease; cytoskeleton; electron microscopy; genetics; human; ileum; inflammatory bowel disease; intestinal absorption; intestinal mucosa; macromolecules; mitochondria; ovalbumin; permeability; sodium caprate; tight junctions; transcytosis; uncoupling agents; Ussing chamber; MEDICINE; MEDICIN;

   Sammanfattning : The study aimed at investigating the intestinal barrier in Crohn's disease, with special reference to epithelial responses to luminal stimuli, and to permeation of proteins.Ileal mucosa from patients undergoing intestinal resection was studied in vitro in Ussing chambers. LÄS MER

5. 4. Barrier function of the Follicle-Associated Epithelium in Stress and Crohn's disease

   Författare :Åsa Keita; Johan D. Söderholm; Ann-Charlott Ericson; Björn Weström; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Corticotropin-releasing hormone; Crohn’s disease; 51Cr- EDTA; Escherichia coli; follicle-associated epithelium; horseradish peroxidase; human; ileum; inflammatory bowel disease; intestinal mucosa; mast cell; M cell; permeability; Peyer’s patches; rat; Ussing chamber; vasoactive intestinal peptide; villus epithelium; Surgery; Kirurgi;

   Sammanfattning : Crohns sjukdom är en kronisk inflammatorisk tarmsjukdom av okänd orsak. Det tidigaste tecknet på Crohns sjukdom är mikroskopiska sår i det s.k. follikelassocierade epitelet (FAE) som täcker ansamlingar av immunceller i tarmen. LÄS MER

7. 5. Studies on nitric oxide in autonomic neurotransmission

   Författare :Caroline Olgart; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :acetylcholine; autonomic neurotransmission; botulinum toxin; colon; guinea pig; ileum; intestine; nitric oxide; rat; tachykinin.;

   Sammanfattning : The aim of the present thesis was to study nitric oxide (NO) as a mediator in autonomic neurotransmission in the enteric nervous system, including studies on the mechanism for neuronal release of NO, as well as the effects of NO on intestinal smooth muscle and enteric neurones. Furthermore, the signal transduction pathway for the evoked effects of NO and nitrergic neurotransmission were investigated. LÄS MER