Sökning: "Il-1β"

Visar resultat 31 - 35 av 165 avhandlingar innehållade ordet Il-1β.

1. 31. Neonatal respiratory control : inspiration, inflammation and the prostaglandin E2 pathway

   Författare :Veronica Siljehav; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Immature or deficient autonomic control is a common problem in infants born at a premature age, and is of central importance in apneas. The pre- and perinatal development of the brainstem neural circuits that control autonomic functions is vital for survival after birth and for the regulation of breathing movements. LÄS MER

3. 32. Toll-like receptor-induced cytokine secretion by human monocytes in healthy donors and septic patients assessed at the single cell level

   Författare :Christian Smedman; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Following the ligation of Toll-like receptors (TLRs) by bacterial-derived signature molecules, innate immune cells such as monocytes, macrophages and neutrophils initiate the inflammatory process by secreting chemokines and cytokines with a wide range of immunomodulatory effects. Under normal conditions, these mediators work to compartmentalize the inflammatory process and eradicate the intruder, while simultaneously recruiting more immune cells to the site of infection. LÄS MER

4. 33. Rheumatoid arthritis as a modifier of periodontitis

   Författare :Letícia Algarves Miranda; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :periodontal disease; attachment loss; juvenile idiopathic arthrtitis; rheumatoid arthritis; interleukin-1β; interleukin-18; elastase;

   Sammanfattning : Periodontitis is a chronic tissue-destructive condition in which the tooth-supporting collagen fibers of ligament and bone are broken down mainly by the host s overreactive immune inflammatory response. The relation between periodontitis and other chronic inflammatory destructive diseases, such as rheumatoid arthritis (RA), has been dealt with in some studies because, in spite of their different etiologies, similar mechanisms of tissue destruction have been described in these conditions. LÄS MER

5. 34. Dexamethasone in horses : safe usage from an anti-doping and medication perspective

   Författare :Carl Ekstrand; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

   Sammanfattning : Equine athletes and companion horses are commonly treated with glucocorticoids such as dexamethasone. Care of sick or injured animals is vital for the animal welfare. To protect the integrity of equine sport, legal therapeutic substances are regulated during competition. LÄS MER

7. 35. The role of caspase-1, caspase-4, NLRP3 and IL-1RA in bladder epithelial cells infected by uropathogenic Escherichia coli

   Författare :Anna Lindblad; Isak Demirel; Manisha Yadav; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urinary tract infection; inflammasome; uropathogenic Escherichia coli; NLRP3; caspase-1; caspase-4; IL-1RA; antimicrobial peptides; estrogen;

   Sammanfattning : Urinary tract infection is one of the most common infections and is mostlycaused by uropathogenic Escherichia coli (UPEC). The inflammasomeassociatedproteins caspase-1, caspase-4 and NLRP3 are essential in the hostcell response during urinary tract infection by regulating IL-1β release. LÄS MER