Sökning: "Il-1β"

Visar resultat 16 - 20 av 139 avhandlingar innehållade ordet Il-1β.

  1. 16. Experimental Studies Aiming to Prevent Type 1 Diabetes Mellitus

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Tobias Rydgren; Uppsala universitet.; [2007]
    Nyckelord :Cell biology; Diabetes; Interleukin-1 trap; Simvastatin; Nitric oxide synthase; Cytokine; Pancreatic islet; Streptozotocin; Transplantation; Cellbiologi;

    Sammanfattning : Type 1 diabetes mellitus (T1DM) is an autoimmune disease in which T-cells and macrophages invade the islets of Langerhans and selectively destroy the insulin producing β-cells, either directly or through the secretion of e.g. cytokines and nitric oxide (NO). This thesis has studied possible strategies to prevent T1DM. LÄS MER

  2. 17. Mycobacterium tuberculosis and the human macrophage shifting the balance through inflammasome activation

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Daniel Eklund; Linköpings universitet.; Linköpings universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Mycobacterium tuberculosis is a very successful pathogen and tuberculosis constitutes a major threat to global health worldwide. The World Health Organization (WHO) estimates that almost nine million new cases and 1. LÄS MER

  3. 18. Cytokine-induced beta-cell apoptosis and its regulation by SOCS-1 and imidazoline compounds

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Molecular Medicine and Surgery

    Författare :Irina Zaitseva; Karolinska Institutet.; Karolinska Institutet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : A selective destruction of pancreatic β-cells as a consequence of inflammation in the islets of Langerhans is a feature of type 1 diabetes. Pro-inflammatory cytokines secreted by T lymphocytes and macrophages infiltrating the pancreatic islets participate in the development of this autoimmune disease by acting directly on the β-cell. LÄS MER

  4. 19. Hormonal regulation of immune modulators in human breast tissue

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Vivian Morad; Linköpings universitet.; Linköpings universitet.; [2015]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Breast cancer is the most common form of cancer and the second leading cause of malignancy-associated death in women worldwide. Estrogens are the main sex hormones in women. LÄS MER

  5. 20. Anti-Collagen Type II Autoantibodies in an Acute Phenotype of Early Rheumatoid Arthritis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mohammed Mullazehi; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Microbiology; immunology; infectious diseases Immunology Clinical immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : Rheumatoid arthritis (RA) is an autoimmune disease with systemic inflammatory features that primarily affects small peripheral joints. Type II collagen (CII), is the most abundant collagen type in joint cartilage. Antibodies against CII (anti-CII) are found in a subpopulation of RA patients. LÄS MER