Sökning: "Il-1β"
Visar resultat 16 - 20 av 165 avhandlingar innehållade ordet Il-1β.
16. Inflammatory response in equine joints : studies on proinflammatory cytokines in diseased joints and chondrocyte cultures
Sammanfattning : Proinflammatory cytokines mediate inflammatory responses as well as regulate tissue metabolism. Thus, they may provide a link between inflammation and other pathologic findings seen in equine joint disease. LÄS MER
17. Chondrocyte and extracellular matrix alterations in equine cartilage during development and inflammation
Sammanfattning : Osteoarthritis (OA) is a disease involving inflammation and subsequent degeneration of joint tissues. The disease progresses with time-dependent stages of degeneration, loss and remodelling of the extracellular matrix (ECM) of articular cartilage, and phenotypical changes in the chondrocytes. LÄS MER
18. Cytokine regulation of pancreatic -cell function with special reference to the pathogenesis of type 1 diabetes
Sammanfattning : Cytokines produced by inflammatory cells have been implicated in the pathogenesis of type 1 diabetes. The overall aim of the present work was to test how different cytokines, supposed to be present in the insulitic lesion, could influence the function of islets of Langerhans. LÄS MER
19. Experimental Studies Aiming to Prevent Type 1 Diabetes Mellitus
Sammanfattning : Type 1 diabetes mellitus (T1DM) is an autoimmune disease in which T-cells and macrophages invade the islets of Langerhans and selectively destroy the insulin producing β-cells, either directly or through the secretion of e.g. cytokines and nitric oxide (NO). This thesis has studied possible strategies to prevent T1DM. LÄS MER
20. Mycobacterium tuberculosis and the human macrophage : shifting the balance through inflammasome activation
Sammanfattning : Mycobacterium tuberculosis is a very successful pathogen and tuberculosis constitutes a major threat to global health worldwide. The World Health Organization (WHO) estimates that almost nine million new cases and 1. LÄS MER