Sökning: "IgE-sensitization"

Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet IgE-sensitization.

  1. 1. IgE sensitization against food allergens : Natural history, relation to airway inflammation and asthma

    Författare :Antonios Patelis; Andrei Malinovschi; Eva Rönmark; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergen components; extract-based; exhaled NO; airway hyperresponsiveness; blood eosinophil count; IgE sensitization; food hypersensitivity; food allergens; perennial allergens; natural history; markers of systemic inflammation; markers of local inflammation; Lungmedicin; Lung Medicine; Fysiologi; Physiology; Immunologi; Immunology;

    Sammanfattning : Background: According to recent studies in children, IgE sensitization not only against perennial allergens, but also against food allergens, is related to asthma risk and increased airway inflammation. During the last decade, a new technique for IgE determination based on allergen components has become available, but its use in epidemiological studies has been limited. LÄS MER

  2. 2. Study of biomarkers for improved diagnosis and therapy monitoring in young asthmatics

    Författare :Nikolaos Tsolakis; Kjell Alving; Lennart Nilsson; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma phenotypes; IgE sensitization; atopy; cat allergen components; exhaled NO; airway hyper-responsiveness; lung function; asthma-related quality of life.;

    Sammanfattning : Background: Type-2 asthma is often related to atopy and is characterized by elevated type-2 biomarkers. However, less is known about the pathophysiology of non-type 2 asthma, factors associated therewith, and the stability of different asthma phenotypes over time. LÄS MER

  3. 3. Nitric Oxide Exchange in Central and Peripheral Airways : Determinants in Health and Respiratory Disease

    Författare :Andrei Malinovschi; Christer Janson; Kjell Alving; Lena Holm; Elisabeth Bel; Uppsala universitet; []
    Nyckelord :exhaled nitric oxide; alveolar NO; bronchial NO flux; extended NO analysis; asthma; smoking; snus; IgE-sensitization; pharyngo-oral tract; nitrate; nitrite; pulmonary hypertension;

    Sammanfattning : Background: Exhaled nitric oxide (NO) is a marker of eosinophilic steroid-sensitive inflammation in the airways of patients with respiratory disease. Moreover, information about the localization of inflammation in the respiratory tree is obtained by estimates of bronchial and alveolar contributions to exhaled NO. LÄS MER

  4. 4. Eczema in childhood and adolescence

    Författare :Emma Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Background: Eczema (atopic dermatitis) is an itchy inflammatory skin disease that affects many children and adolescents. Eczema associated with IgE antibodies is called atopic eczema (AE), while other eczema is called nonatopic eczema (non-AE). Having a filaggrin (FLG) mutation is associated with increased risk for eczema. LÄS MER

  5. 5. Microbial and maternal influences on allergic sensitization during childhood: defining a role for monocytes

    Författare :Shanie Saghafian Hedengren; Eva Sverremark-Ekström; Susan Prescott; Stockholms universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; allergic sensitization; maternal allergy; Toll-like receptor; p38-MAPK; IL-6; Epstein-Barr virus; early-life microbial exposure; NK cells; IFN-γ; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : Allergic diseases are influenced by genetics and the environment. Maternal allergy appears to confer a higher risk for allergic sensitization than paternal allergy, suggesting an in utero influence. LÄS MER