Sökning: "IgE sensitisation"
Visar resultat 21 - 25 av 25 avhandlingar innehållade orden IgE sensitisation.
21. Molecular characterisation of major allergens from mite (Lep d 2) and cat (Fel d 1)
Sammanfattning : The prevalence of allergic disease has increased significantly during the last decades and today more than 30% of the Swedish population is affected. By using recombinant allergens, diagnostics and treatment can be improved and the mechanisms of allergic reactions may be further explored. LÄS MER
22. Development of IgG subclass antibodies to allergens in early childhood
Sammanfattning : Background: Immune responses to allergens in young children include both Thl and Th2 like immunity, which may regulate the secretion of IgG subclass antibodies differently. The time, route and level of exposure to an allergen, as well as maternally transferred immunity, may be decisive whether sensitisation or tolerance will ensue. LÄS MER
23. Genetic studies of candidate genes in eczema
Sammanfattning : Eczema is a common inflammatory skin disorder characterised by itching and relapsing eczematous lesions. It usually presents in early childhood and affects about 10-20% of all children. The background is multifactorial, with both environmental risk factors and hereditary factors contributing to the development of the disease. LÄS MER
24. Immune maturation and modulation in childhood allergies : Aspects of epigenetic, mucosal and systemic immune mediators in allergy development and prevention
Sammanfattning : The prevalence of allergic diseases has in the past century increased among children in affluent societies. Underlying causes are incompletely disentangled, but decreased diversity in environmental and microbial exposures could drive allergy development. LÄS MER
25. Interactions between mast cells and smooth muscle in asthma models
Sammanfattning : Allergic asthma is the major phenotype of asthma and is characterized by specific responses to allergens as well as airway hyperresponsiveness (AHR), inflammation and remodelling. Mast cells and airway smooth muscle cells (ASM) play an important role in the allergic airway response and there are several indications that a cross-talk exists between these two cell types contributing to asthma pathogenesis. LÄS MER