Sökning: "Idiopathic pulmonary fibrosis IPF"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Idiopathic pulmonary fibrosis IPF.

  1. 1. Tissue remodelling in pulmonary fibrosis linked to 5-HT2 receptor activation

    Författare :Anna Löfdahl; Lungbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Serotonin 5HT ; Serotonin class 2 receptor antagonist; Fibroblast; Pulmonary fibrosis; Extracellular matrix ECM ;

    Sammanfattning : After an injury, an immediate reparative response is triggered to replace the damaged tissue, however, in fibrosis, cells remain active despite wound resolution causing a steady build-up of fibrotic tissue. In pulmonary fibrosis,there is a constant regeneration and remodelling of lung tissue where the thin architecture of alveoli become thickened, hampering efficient diffusion of oxygen, as seen in diseases like idiopathic pulmonary fibrosis (IPF). LÄS MER

  3. 2. Alveolar Progenitor Cells in Lung Damage and Regeneration in Pulmonary Fibrosis

    Författare :Victoria Ptasinski; NanoLund: Centre for Nanoscience; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; idiopathic pulmonary fibrosis IPF ; alveolar epithelium; aberrant basaloid cells; bleomycin model; induced pluripotent stem cells;

    Sammanfattning : .... LÄS MER

  4. 3. Remodeling of airway epithelium and lung extracellular matrix in COPD and IPF

    Författare :Ulf Hedström; Lungbiologi; []
    Nyckelord :Chronic obstructive pulmonary disease; Idiopathic pulmonary fibrosis; Extracellular matrix; Epithelial cells; Remodeling;

    Sammanfattning : .... LÄS MER

  5. 4. Idiopathic pulmonary fibrosis : disease presentation, clinical course and potential biomarkers

    Författare :Dimitrios Kalafatis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The interest and research within the area of the fatal lung disease idiopathic pulmonary fibrosis (IPF) has increased exponentially over the past decades. This has resulted in important insights into the nature and pathogenesis of the disease, which ultimately constitute the knowledge base upon which diagnostic, management, treatment decisions and guidelines are shaped. LÄS MER

  7. 5. Causes and treatment of chronic respiratory failure : experience of a national register

    Författare :Torbjörn Gustafson; Kerstin Ström; Karl Franklin; Kjell Torén; Kurt Boman; Leif Bjermer; Umeå universitet; []
    Nyckelord :Internal medicine; Invärtesmedicin; chronic obstructive pulmonary disease; pulmonary fibrosis; kyphoscoliosis; respiratory failure; sex; smoking; occupation; survival; long-term oxygen therapy; mechanical ventilation; lungmedicin; Lung Medicine;

    Sammanfattning : Long-term oxygen therapy (LTOT) or home mechanical ventilation (HMV) can improve survival time in chronic respiratory failure. A national quality register could be an aid to identifying risk markers and optimizing therapy for respiratory failure. LÄS MER