Sökning: "Ida E. Andersson"

Hittade 3 avhandlingar innehållade orden Ida E. Andersson.

  1. 1. Modified Glycopeptides Targeting Rheumatoid Arthritis : Exploring molecular interactions in class II MHC/glycopeptide/T-cell receptor complexes

    Författare :Ida E. Andersson; Jan Kihlberg; Anna Linusson Jonsson; Craig Crews; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Major histocompatibility complex; class II MHC; T-cell receptor; rheumatoid arthritis; collagen-induced arthritis; glycopeptide; amide bond isostere; comparative modeling; rational design; molecular docking; molecular dynamics simulation; statistical molecular design; Bioorganic chemistry; Bioorganisk kemi; organisk kemi; Organic Chemistry; Biorganic Chemistry; bioorganisk kemi; datorlingvistik; computational linguistics;

    Sammanfattning : Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that leads to degradation of cartilage and bone mainly in peripheral joints. In collagen-induced arthritis (CIA), a mouse model for RA, activation of autoimmune CD4+ T cells depends on a molecular recognition system where T-cell receptors (TCRs) recognize a complex between the class II MHC Aq protein and CII259-273, a glycopeptide epitope from type II collagen (CII). LÄS MER

  2. 2. Occurrence of Traffic-Derived Microplastics in Different Matrices in the Road Environment

    Författare :Ida Järlskog; Yvonne Andersson-Sköld; Stephan Wagner; Statens väg- och transportforskningsinstitut; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; non-exhaust particles; tire wear particles; road dust; automated SEM EDX; environmental samples; optimized sample preparation; organic pollutants; street sweeping; traffic-derived microplastics; road simulator;

    Sammanfattning : The prevalence of microplastic contamination has raised concerns about the potential risk and impact on the global environment. Traffic-derived microplastics, i.e., tire wear particles (TWP), polymer-modified bitumen, and road markings contribute to the emissions, and TWP are assumed to be one of the largest sources of microplastic emissions. LÄS MER

  3. 3. Borehole Thermal Energy Storage Systems for Storage of Industrial Excess Heat : Performance Evaluation and Modelling

    Författare :Emil Nilsson; Patrik Rohdin; Maria Andersson; Mathias Cehlin; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : Improving industrial energy efficiency is considered an important factor in reducing carbon dioxide emissions and counteract climate change. For many industrial companies in cold climates, heat generated at the site in summer will not be needed to fulfil the site heat demand during this time, and is thus removed to the outdoor air. LÄS MER