Sökning: "IRS"

Visar resultat 1 - 5 av 58 avhandlingar innehållade ordet IRS.

1. 1. Identification of abnormally expressed genes in skeletal muscle contributing to insulin resistance and type 2 diabetes

   Författare :Xudong Huang; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; gene expression; high-fat intake; RT-PCR; mitochondrial genes; cathepsin L; Shc; IRS-2; IRS-1; GS; cDNA differential display; Insulin resistance; type 2 diabetes; sekretion; diabetologi;

   Sammanfattning : The metabolic defects of insulin resistance and type 2 diabetes can result from changes in gene expression and protein functions due to genetic and environmental influences. The aim of this study was to identify abnormally expressed genes associated with insulin resistance or type 2 diabetes, and further to test whether possible defects are inherited or acquired. LÄS MER

3. 2. Beyond Massive MIMO : Trade-offs and Opportunities with Large Multi-Antenna Systems

   Författare :Juan Vidal Alegría; Kommunikationsteknologi; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MIMO; massive MIMO; cell-free massive MIMO; Decentralized multi-antenna architectures; Decentralized schemes; WAX decomposition; LIS; Reconfigurable surfaces; RIS; IRS; ARIS; FRIS;

   Sammanfattning : After the commercial emergence of 5G, the research community is already putting its focus on proposing innovative solutions to enable the upcoming 6G. One important lesson put forth by 5G research was that scaling up the conventional multiple-input-multiple-output (MIMO) technology by increasing the number of antennas could be extremely beneficial for effectively multiplexing data streams in the spatial domain. LÄS MER

4. 3. Fat cell insulin resistance : an experimental study focusing on molecular mechanisms in type 2 diabetes

   Författare :Frida Renström; Jan Eriksson; Anna Krook; Umeå universitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; adipocyte; insulin signaling; insulin; glucose; IRS-1; glucose uptake; insulin resistance; typ 2 diabetes; serum; Medicine; Medicin;

   Sammanfattning : The aim of the present thesis was to further increase our understanding of mechanisms contributing to and maintaining cellular insulin resistance in type 2 diabetes (T2D). For this reason, the effects of high glucose and insulin levels on glucose transport capacity and insulin signaling, with emphasis on insulin receptor substrate 1 (IRS-1) were assessed in fat cells. LÄS MER

5. 4. Signal Processing Aspects of Massive MIMO and IRS-Aided Communications

   Författare :Özgecan Özdogan; Emil Björnson; Erik G. Larsson; Mari Kobayashi; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

   Sammanfattning : The data traffic in cellular networks has grown at an exponential pace for decades. This trend will most probably continue in the future, driven by new innovative applications. One of the key enablers of future cellular networks is the massive MIMO technology, and it has been started to be commercially deployed in many countries. LÄS MER

7. 5. Molecular characterization of insulin resistance in the adipose tissue and the effects of thiazolidinediones

   Författare :Ann Hammarstedt; Göteborgs universitet; []
   Nyckelord :IRS-1; PGC-1; adiponectin; insulin resistance; TZD;

   Sammanfattning : Type 2 diabetes is the most common metabolic disorder today and has reached epidemic proportions in many contries. Insulin resistance plays a central role in the pathogenesis of Type 2 diabetes and can be present for a decade or more before onset of the disease. LÄS MER