Sökning: "INR variability"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden INR variability.
1. Anticoagulation treatment in patients with a mechanical heart valve
Sammanfattning : BackgroundEvery year about 2,500 patients in Sweden undergo surgery for heart valve disease, primarily in the aortic valve. In contrast to the mitral valve, which can be repaired in 70% of the cases, the aortic valve is normally replaced by a mechanical or biological prosthesis. LÄS MER
2. Warfarin treatment quality in stroke prevention
Sammanfattning : BackgroundIschemic stroke is a serious condition often associated to presence of atrial fibrillation (AF). Use of anticoagulants for AF patients greatly reduces the risk of stroke. Warfarin is the most commonly used anticoagulant in Sweden. The aim of this thesis was to study the impact of warfarin treatment quality in Swedish stroke prevention. LÄS MER
3. Pharmacometric Models for Individualisation of Warfarin in Adults and Children
Sammanfattning : Warfarin is one of the most widely used anticoagulants. Therapy is complicated by warfarin’s narrow therapeutic range and pronounced variability in individual dose requirements. Although warfarin therapy is uncommon in children, it is crucial for children with certain congenital or acquired heart diseases. LÄS MER
4. Efficacy and safety of warfarin treatment in venous thromboembolic disease
Sammanfattning : BackgroundAs a major cause of morbidity and mortality treatment of venous thromboembolism is important, with the correct use of anticoagulants it is possible to greatly reduce both mortality and morbidity. Warfarin is among the most widely used anticoagulants being effective in treatment and prevention of venous thromboembolism with few negative side effects other than bleeding complications. LÄS MER
5. Monitoring of the oral anticoagulants apixaban and rivaroxaban to optimize individual safety and efficacy
Sammanfattning : The oral anticoagulants apixaban and rivaroxaban are administered at fixed doses without requiring routine monitoring. However, there is a dose and exposure dependency in efficacy and safety, and monitoring the anticoagulants may improve treatment outcomes. LÄS MER