Sökning: "INR prothrombin"

Hittade 4 avhandlingar innehållade orden INR prothrombin.

  1. 1. Studies on warfarin treatment with emphasis on inter-individual variations and drug monitoring

    Författare :Abdimajid Osman; Tomas Lindahl; Peter Söderkvist; Marja-Liisa Dahl; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Warfarin; VKORC1; Haplotype; Prothrombin time; INR; Clinical chemistry; Klinisk kemi;

    Sammanfattning : Waran används sedan 60 år som blodförtunnande läkemedel för att förebygga eller förhindra progress av blodproppssjukdom. I Sverige behandlas årligen cirka 1 % av befolkningen med waran. I Östergötland uppskattas antal waranpatienter till cirka 3000. Waran hämmar enzymet VKORC1 som ansvarar för vitamin K omsättningen i kroppen. LÄS MER

  3. 2. Venous thromboembolism. Aspects on risk factors, diagnostic tools and treatment with thrombin inhibition

    Författare :Karin Wåhlander; Göteborgs universitet; []
    Nyckelord :deep vein thrombosis; pulmonary embolism; venous thromboembolism; Factor V Leiden; prothrombin gene G20210A; thrombin inhibition; ximelagatran; melagatran; PT; APTT; D-dimer.;

    Sammanfattning : Venous thromboembolism (VTE), comprising deep vein thrombosis (DVT) and pulmonary embolism (PE), is a multifactorial disease. The aims of the present thesis were to investigate Factor V Leiden and prothrombin G20210A mutations as potential risk factors for VTE during and after major surgery, to compare different D-dimer assays and evaluate their usefulness in the diagnosis of DVT, to investigate clinical effects, safety and pharmacokinetic properties of an oral thrombin inhibitor (ximelagatran) when treating VTE and finally to investigate the usefulness of coagulation assays (APTT and PT) during treatment with thrombin inhibition. LÄS MER

  4. 3. Management of Adults with Congenital Heart Disease

    Författare :Daniel Samarai; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adults with Congenital Heart Disease; Congenital Heart Disease; Congenital heart defect CHD ; Anticoagulation; Anticoagulants; anticoagulant treatment; Thromboembolic events; Major bleeding; Diagnostic Imaging methods;

    Sammanfattning : Adults with congenital heart disease (ACHD) are a completely new and rapidly growing specialty comprising patients who require specialist knowledge regarding their care and treatment. Challenges involve diagnostics and treatment as studies are scarce and include small and heterogenous study populations. LÄS MER

  5. 4. Complications in trochanteric and subtrochanteric femoral fractures

    Författare :Leif Mattisson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The hip fracture is a major public health problem. The majority of hip fracture patients are elderly with comorbidities and there is a strong association with osteoporosis, especially for the extracapsular (trochanteric and subtrochanteric) types of fractures. LÄS MER