Sökning: "IL-6"

Visar resultat 6 - 10 av 471 avhandlingar innehållade ordet IL-6.

  1. 6. Metabolic effects of interleukin-6

    Författare :Ingrid Wernstedt; Göteborgs universitet.; Gothenburg University.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-6; cytokine; obesity; energy expenditure; lipolysis; ASP; sympathetic nervous system; exercise; -174 G C IL-6 polymorphism; fat mass; stress response; cerebrospinal fluid;

    Sammanfattning : The levels of the cytokine interleukin-6 (IL-6) in the circulation are positively correlated with indices of obesity and metabolic disturbances. Paradoxically, plasma IL-6 levels increase markedly during prolonged and strenuous exercise, mainly due to increased production and release from working skeletal muscle. LÄS MER

  2. 7. Insulin-like Growth Factor-I (IGF-I) and Interleukin-6 (IL-6) regulate body fat

    Detta är en avhandling från Göteborg

    Författare :Kristina Wallenius; Göteborgs universitet.; Gothenburg University.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; insulin-like growth factor I IGF-I ; interleukin-6 IL-6 ; growth hormone GH ; GH releasing factor GHRF ; GH secretagogue GHS ; receptor; leptin; insulin; glucose; intracerebroventricular ICV ; dual-energy X-ray absorptiometry DXA ; indirect calorimetry.;

    Sammanfattning : The aim of this thesis was to investigate the role of insulin-like growth factor-I (IGF-I) and interleukin-6 (IL-6) in the regulation of metabolism and body fat mass. Circulating IGF-I is mainly liver derived, while a large part of circulating IL-6 is produced by adipose tissue. LÄS MER

  3. 8. Inhibition of WNT5A Signaling and Function in Malignant Melanoma

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Rickard Linnskog; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; WNT5A; Malignant Melanoma; Migration; Invasion; TGFβ; IL-6; p38-MAPK;

    Sammanfattning : The life-threatening disease of malignant melanoma is one of the fastest growing forms of cancer, affecting an estimated number of 200,000 patients worldwide every year. Although highly curable if detected early, once the melanoma has metastasized there are few treatment options and a median survival rate of only 6-9 months. LÄS MER

  4. 9. Effects of cytokines on preadipocyte differentiation and Wnt signalling

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Birgit Gustafson; Göteborgs universitet.; Gothenburg University.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adipocyte differentiation; adiponectin; beta-Catenin; C EBPalpha; IL-6; PPARgamma; TNFalpha; Wnt signalling;

    Sammanfattning : The relationship between amount of adipose tissue, the Metabolic Syndrome and Type 2 diabetes has been recognized for several years. However, the mechanisms for this remain to be clarified. Not all obese individuals develop insulin resistance or Type 2 diabetes and these perturbations are also seen in non-obese individuals. LÄS MER

  5. 10. Cytokines in Metabolic Functions

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Anna Benrick; Göteborgs universitet.; Gothenburg University.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-1; IL-6; LIF; obesity; fat mass; energy expenditure; hypothalamus; gp130 SNP; myocardial infarction;

    Sammanfattning : During infections, circulating cytokines are largely produced by immune cells. In healthy obese individuals, large parts of these circulating cytokines are produced in adipose tissue, for instance by macrophages that have accumulated there. LÄS MER