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Visar resultat 1 - 5 av 17 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Regulatory Immune Responses and Repair Mechanisms in Atherosclerosis

    Författare :Sara Rattik; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Cardiovascular disease; T helper 2 cells; ApoB100; Regulatory B cells; Regulatory T cells; Smooth muscle cells; IL-22.;

    Sammanfattning : Atherosclerosis is a chronic inflammatory disease characterized by the formation of lipid rich plaques in the arterial wall. Rupture of a plaque results in clinical manifestations such myocardial infarction or stroke. LÄS MER

  3. 2. The IL-23 axis and innate immunity in the airways

    Författare :Marit Stockfelt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-23; airways;

    Sammanfattning : The Interleukin-23 (IL-23) axis is a communication system that integrates innate and adaptive immunity. When triggered by microbial stimuli, antigen presenting cells can secrete the cytokine IL-23, leading to the production of IL-17 and IL-22. LÄS MER

  4. 3. Interleukin-22 binding protein in multiple sclerosis and experimental inflammation models

    Författare :Hannes Lindahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is the leading cause of non-traumatic neurological disability in young adults. Although the cause of the disease is unknown, several genetic and environmental risk factors have been identified. LÄS MER

  5. 4. Atherosclerotic Plaque Stability and Vascular Repair

    Författare :Anki Knutsson; Kärlväggsbiologi; []
    Nyckelord :atherosclerosis; diabetes; repair; inflammation; extracellular matrix;

    Sammanfattning : Myocardial infarction and stroke are two of the most common causes of death in the world, mainly caused by a rupture of an atherosclerotic plaque. A vulnerable atherosclerotic plaque is a high-risk plaque that can form a thrombus by rupture. LÄS MER

  7. 5. Lactobacillus mediated delivery of therapeutic peptides in the gastrointestinal tract

    Författare :Yin Lin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lactobacilli are normal residents of the human gastrointestinal (GI) tract. Many species belonging to the genera Lactobacillus with health beneficial properties have been introduced as probiotics. Genetic engineering of Lactobacillus could potentially combine the colonizing ability and probiotic effect with an engineered therapeutic function. LÄS MER