Sökning: "IL-2 receptor"

Visar resultat 16 - 20 av 83 avhandlingar innehållade orden IL-2 receptor.

  1. 16. Immune dysregulation in HIV-1 infected lymphoid tissue

    Författare :Homira Behbahani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; HAART; cytokines; chemokines; lymphoid tissue; perforin; Nef; LIF; placenta; chemokine receptor;

    Sammanfattning : Lymphoid compartments are major sites for HIV-1 replication. We evaluated cytokines, chemokines and immunological effector function at the single cell level in lymphoid tissues in chronically HIV-1 infected patients. LÄS MER

  2. 17. Studies of the immunopathogenesis in three arthritis models in rats

    Författare :Helena Erlandsson Harris; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :experimental arthritis; inflammation; adjuvants; T-cell receptor; collagen type II; cartilage oligomeric matrix protein COMP ;

    Sammanfattning : The immunopathogenesis of three arthritis models has been studied; oil-induced arthritis (OIA), homologous collagen-induced arthritis (CIA) and COMP-induced arthritis. The induction of a monophasic arthritis, OIA, in the DA rat with a single intradermal injection of Freund's incomplete adjuvant (FIA) was reported. LÄS MER

  3. 18. Regulation of T cells in Atherosclerosis

    Författare :Megan Mulholland; Kardiovaskulär forskning - cellulär metabolism och inflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Atherosclerosis, the underlying pathology of cardiovascular diseases such as myocardial infarction and ischemic stroke, is characterized by chronic inflammation. T cells are present in atherosclerotic plaques and have been implicated in its pathogenesis. LÄS MER

  4. 19. An experimental study on the interaction between the neuro-endocrine and immune systems in the gastrointestinal tract

    Författare :Bi-Feng Qian; Eva Ekblad; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gastrointestinal tract; neuro-endocrine system; substance P; vasoactive intestinal polypeptide; vagus nerves; mucosal immune system; T lymphocytes; cytokines; inflammation; mouse;

    Sammanfattning : The mucosa lining of the gastrointestinal (GI) tract is in immediate contact with food nutrients to allow a rapid and efficient digestion and absorption and at the same time protects against the incessant risk of attack from pathogenic microbes. Maintenance of normal physiological activities in the GI tract is dependent on a number of regulatory interactions between the nervous, endocrine, and immune systems, as well as environmental and genetic factors. LÄS MER

  5. 20. CTLA-4 expression, regulation and associations in autoimmune myasthenia gravis

    Författare :XiongBiao Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cytotoxic-T-lymphocyte-associated antigen 4 CTLA-4 ; Myasthenia gravis MG ; Immune inhibitory receptor; Autoimmune disease; Genetic polymorphism.;

    Sammanfattning : Myasthenia gravis (MG) is a neuromuscular disease with muscle weakness due to an autoimmune attack against the nicotinic acetylcholine receptor (nAChR) on the skeletal muscle endplate. Cytotoxic-T-lymphocyte-associated antigen 4 (CTLA-4) plays a global inhibitory role in the immune system and has a crucial role in autoimmunity. LÄS MER