Sökning: "IL-18"

Visar resultat 11 - 15 av 63 avhandlingar innehållade ordet IL-18.

  1. 11. Immunomodulation and its effector mechanisms in atherosclerosis

    Författare :Charlotta Hjerpe; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is a disease of the arterial intima, characterized by cholesterol deposition, inflammation and fibrosis. The pathogenesis of atherosclerosis is related to both innate and adaptive immune responses, and modulation of immune reactions in animal models of atherosclerosis affects the progression of the disease. LÄS MER

  3. 12. Intestinal dendritic cell migration and induction of T cell responses

    Författare :Karin Hägerbrand; Adaptivt immunförsvar; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The intestine represents the body’s largest surface exposed to the outer world and is thus a major entry site for pathogens such as bacteria and viruses. The intestinal immune system has the important task of protecting us against infection while maintaining tolerance against the vast amount of commensal microbes populating the intestinal tract and the multitude of foreign antigen present in the diet. LÄS MER

  4. 13. Non-invasive ultrasound-based cardiovascular imaging in mouse models of atherosclerosis

    Författare :Julia Grönros; Göteborgs universitet; []
    Nyckelord :atherosclerosis; ultrasound-based imaging; cardiovascular disease; coronary artery; mouse; color Doppler echocardiography; ultrasound biomicroscopy; statin;

    Sammanfattning : Atherosclerosis is a chronic multi-factorial vascular disease. It generally requires large clinical settings and over many years to study the disease progression in man. Genetically modified mouse models of atherosclerosis have dramatically increased research feasibility within this area. LÄS MER

  5. 14. Infectious and inflammatory mechanisms in preterm birth and cerebral palsy

    Författare :Bo Jacobsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; preterm birth; preterm labor; preterm prelabor rupture of membranes; intra-uterine infection; intra-amniotic inflammation; interleukin-6; interleukin-8; interleukin-18; monocyte chemotactic protein-1; cerebral palsy; antenatal risk factors; chorioamnionitis.;

    Sammanfattning : Background: International studies of women in preterm labor (PTL) and preterm pre-labor rupture of the membranes (pPROM) have shown a significant association between microbial invasion of the amniotic cavity (MIAC), some cytokines and chemokines and preterm birth (PTB). These studies have been performed in countries with higher incidence of PTB than that in Sweden. LÄS MER

  7. 15. Modulation of invariant NKT cell activity by cytokines and receptors in human disease

    Författare :Carlotta Kuylenstierna; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Invariant natural killer T (NKT) cells are innate-like lymphocytes with both immunoregulatory and cytotoxic functions that play a role as activators and regulators of the immune response in many diseases. NKT cells are believed to bridge the innate and adaptive immune systems by rapidly producing large quantities of cytokines after recognition of CD1d-presented lipid antigens. LÄS MER