Sökning: "IL-12"

Visar resultat 11 - 15 av 131 avhandlingar innehållade ordet IL-12.

  1. 11. Experimental Chagas disease

    Författare :John Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Trypanosoma cruzi; NK cells; cytotoxicity; IFN-gamma; IL-12; IFN-alpha beta; Chagas disease; polymyositis; myocarditis; genotype dependence and Toll-like receptors.;

    Sammanfattning : The main focus of this thesis was to develop and utilise experimental models using the protozoan parasite Trypanosoma cruzi. We were especially interested in studying the activation of NK cells early after T. cruzi infection and what factors that predispose to a chronic inflammatory disease after T. cruzi infection. LÄS MER

  3. 12. Immune regulation in multiple sclerosis : cytokines and metalloproteinases

    Författare :Volkan Özenci; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immunological mechanisms play a central role in the pathogenesis sclerosis (MS). In this study two groups of related immune variables are cytokines and metalloproteinases (MMPs), which regulate each other's production and activation. LÄS MER

  4. 13. Allergic airway inflammation and bone marrow eosinophilopoiesis. Modulation by cytokines

    Författare :Lin-Ling Zhao; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergy; airway inflammation; cytokine; eosinophil; eosinophilopoiesis;

    Sammanfattning : Accumulation of eosinophils in the airways and lung parenchyma is one of the hallmarks of allergic airway inflammation. This cellular inflammatory response is likely to involve the release of eosinophils from peripheral storage pools and possibly cause production of eosinophils in the bone marrow (BM). LÄS MER

  5. 14. Organic dust from pig environment induces activation of human T cells

    Författare :Charlotte Müller-Suur; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Organic dust; T cells; NK cells; cytokines; cellular activation;

    Sammanfattning : Farmers suffer more frequently from inflammatory airway disorders than the population in general and a ongoing airway inflammation has been shown also in symptom-free healthy farmers. Exposure in a swine confinement building causes an intense airway inflammation with recruitment of inflammatory cells, predominately neutrophils, in healthy, previously, non-exposed subjects. LÄS MER

  7. 15. Maturation of T-lymphocytes and monocytes in children in relation to development of atopic disease

    Författare :Helena Aniansson Zdolsek; Örjan Stranne; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Bakgrund: Atopiska sjukdomar har ökat i västvärlden under de senaste årtiondena. För att förstå den bakomliggande mekanismen vid sensibilisering mot allergen behöver vi förbättra vår kunskap av T-lymfocyters och monocyters utmognad hos små bam. LÄS MER