Sökning: "IL-1β"
Visar resultat 21 - 25 av 165 avhandlingar innehållade ordet IL-1β.
21. Cytokine-induced beta-cell apoptosis and its regulation by SOCS-1 and imidazoline compounds
Sammanfattning : A selective destruction of pancreatic β-cells as a consequence of inflammation in the islets of Langerhans is a feature of type 1 diabetes. Pro-inflammatory cytokines secreted by T lymphocytes and macrophages infiltrating the pancreatic islets participate in the development of this autoimmune disease by acting directly on the β-cell. LÄS MER
22. Hormonal regulation of immune modulators in human breast tissue
Sammanfattning : Breast cancer is the most common form of cancer and the second leading cause of malignancy-associated death in women worldwide. Estrogens are the main sex hormones in women. LÄS MER
23. Anti-Collagen Type II Autoantibodies in an Acute Phenotype of Early Rheumatoid Arthritis
Sammanfattning : Rheumatoid arthritis (RA) is an autoimmune disease with systemic inflammatory features that primarily affects small peripheral joints. Type II collagen (CII), is the most abundant collagen type in joint cartilage. Antibodies against CII (anti-CII) are found in a subpopulation of RA patients. LÄS MER
24. Regulation of cytokine-induced nitric oxide production in insulin-producing cells
Sammanfattning : Cytokine-induced expression of the inducible form of nitric oxide synthase (iNOS) and production of nitric oxide (NO) may contribute to pancreatic β-cell damage during the development of type 1 diabetes. iNOS catalyses the conversion of arginine into citrulline and NO, a reaction regulated by the amount of expressed iNOS enzyme and by the cellular availability of arginine. LÄS MER
25. Monocyte and Neutrophil Inflammatory Responses to the Periodontopathogen Porphyromonas gingivalis
Sammanfattning : Periodontitis is one of the most common adult infections. Duing bacteremia in healthy individuals or patients with chronic periodontitis, a number of oral bacteria such as Porphyromonas gingivalis encounter inflammatory cells in the blood eg. platelets, neutrophils and monocytes. LÄS MER