Sökning: "IKr"

Visar resultat 6 - 7 av 7 avhandlingar innehållade ordet IKr.

1. 6. Role of the hERG-channel in arrhythmia and teratogenicity : studies in animal models and the human embryonic heart

   Författare :Christian Danielsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Drugs that inhibit cardiac repolarization are associated with potentially life threatening side effects in the form of ventricular arrhythmias in humans. Animal studies show that this mechanism also is relevant for the embryo, and that the circulatory depression results in hypoxia with embryotoxicity in the form of malformations and death as a consequence. LÄS MER

3. 7. Risks and risk monitoring in sotalol therapy for atrial fibrillation

   Författare :Hanna Lenhoff; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Atrial fibrillation (AF) stands as the most prevalent arrhythmia, significantly impacting both the prognosis and symptomatology of affected individuals. Healthcare expenditures associated with AF treatment and its related complications, in terms of morbidity and mortality, are substantial. LÄS MER