Sökning: "III -NOM complexes"

Visar resultat 11 - 15 av 334 avhandlingar innehållade orden III -NOM complexes.

  1. 11. DNA-Mediated Detection and Profiling of Protein Complexes

    Författare :Maria Hammond; Ulf Landegren; Masood Kamali-Moghaddam; Christof Niemeyer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proximity ligation assay; Protein complexes; Protein interactions; Biomarkers; Prions; Antibodies; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Proteins are the effector molecules of life. They are encoded in DNA that is inherited from generation to generation, but most cellular functions are executed by proteins. Proteins rarely act on their own – most actions are carried out through an interplay of tens of proteins and other biomolecules. LÄS MER

  3. 12. On the immunopathogenesis of systemic lupus erythematosus - Immune complexes, type I interferon system, complement system and platelets

    Författare :Christian Lood; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; systemic lupus erythematosus; autoimmunity; rheumatology; immunology; cardiovascular disease;

    Sammanfattning : Systemic lupus erythematosus (SLE) is an autoimmune rheumatic disorder characterized by inflammation in several organ systems. SLE patients have an impaired ability to clear dying cells which leads to the exposure of several nuclear antigens which might break self tolerance. LÄS MER

  4. 13. Platelets and their immunomodulatory roles during Streptococcus pyogenes infection

    Författare :Sinead Hurley; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Sepsis and invasive bacterial infection is a major cause of human disease and death worldwide. Streptococcus pyogenes is one of the major pathogens responsible for bacterial infections, which range from mild to severe and life threatening conditions. S. LÄS MER

  5. 14. Asymmetric Hydrogenations : Syntheses of Ligands and Expansion of Substrate Scope

    Författare :Pradeep Cheruku; Pher Andesson; Jay Siegel; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Catalysis; Asymmetric; Hydrogenations; Reductions; Olefins; Imines; Enol phosphinates; Transition metal; Complexes; Iridium; Enamines; Ruthenium; Ligands; Trifluoromethyl; Diphenylvinylphosphine oxides; Vinyl phosphonates; Chemistry; Kemi;

    Sammanfattning : Asymmetric hydrogenation has emerged as a versatile methodology to obtain a wide range of chiral precursors. This thesis focused on the synthesis of new chiral ligands and the expansion of the substrate scope of asymmetric hydrogenations. LÄS MER

  7. 15. Reaction Mechanisms of Metalloenzymes and Synthetic Model Complexes Activating Dioxygen : A Computational study

    Författare :Valentin Georgiev; Per E.M. Siegbahn; Sam de Visser; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; catalysis; density functional theory; extradiol; intradiol; dioxygenases; oxygen; biomimetic complexes; heme; spin transition; adipic acid; Chemical physics; Kemisk fysik; kvantkemi; Quantum Chemistry;

    Sammanfattning : Quantum chemistry has nowadays become a powerful and efficient tool that can be successfully used for studies of biosystems. It is therefore possibleto model the enzyme active-site and the reactions undergoing into it, as well as obtaining quite accurate energetic profiles. LÄS MER