Sökning: "IHPD"

Hittade 2 avhandlingar innehållade ordet IHPD.

1. 1. Molecular Mechanisms Underlying Abnormal Placentation in the Mouse

   Författare :Yang Yu; Reinald H. Fundele; Rolf Ohlsson; J. GRAHAM BURTON; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; IUGR; Placental phenotype; Placental hyperplasia; Diabetes; IHPD; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi;

   Sammanfattning : Placental development can be disturbed by various factors, such as mutation of specific genes or maternal diabetes. Our previous work on interspecies hybrid placental dysplasia (IHPD) and two additional models of placental hyperplasia, cloned mice and Esx1 mutants, showed that many genes are deregulated in placental dysplasia. LÄS MER

3. 2. New Functions for Old Genes in the Mouse Placenta

   Författare :Umashankar Singh; Reinald Fundele; Anne C Ferguson-Smith; Uppsala universitet; []
   Nyckelord :Developmental biology; hybrid dysgenesis effects; placental hyperplasia; functional screening; giant cell; glycogen cell; Utvecklingsbiologi;

   Sammanfattning : Different species are separated by pre-zygotic reproductive barriers which impede gene flow between them. Rarely, when pre-zygotic barriers break down, interspecific hybrids are produced that display abnormal phenotypes, collectively called hybrid dysgenesis effects. LÄS MER