Sökning: "IFN-gamma"

Visar resultat 21 - 25 av 155 avhandlingar innehållade ordet IFN-gamma.

  1. 21. The role of interferons in the resistance to infection with Chlamydia pneumoniae

    Författare :Christian Trumstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chlamydia pneumoniae is an obligate intracellular bacterial pathogen that infects the respiratory tract in human. IFN-gamma is an essential cytokine for the immune response triggered to limit infection with C. pneumoniae. C. LÄS MER

  3. 22. In vitro studies on human first trimester forebrain cells : differentiation and interactions with immunoregulating molecules

    Författare :Alyaa Mohammed Ali Mousa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis has focused on understanding, at the molecular level, growth regulation and differentiation of human first trimester forebrain cells, and the immune signals mediating these processes. Primary cultures were established from human forebrain tissue derived from elective first trimester abortions. LÄS MER

  4. 23. Potential role of anti-cytokine autoantibodies in the regulation of cytokine responses in infections and autoimmune diseases

    Författare :Rihab Abdel Magid Awad El Karim; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cytokines; autoantibodies; MS; AM; ST; MGUS; GBS; lower respiratory tract infection; mAbs;

    Sammanfattning : Anti-cytokine autoantibodies are serum proteins that bind cytokines and specifically interfere with measurements and biological activities of the corresponding cytokines. Plasma, sera, and CSF were obtained from patients with multiple sclerosis (MS), aseptic meningitis (AM), stroke (ST), and polyneuropathy, Guillain Barré Syndrome (GBS). LÄS MER

  5. 24. Cytokine-modulated dendritic cell immunotherapy in autoimmune diseases

    Författare :Sanjaya Bandara Adikari; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Autoimmunity is the result of failure of self-tolerance processes. When the immune system fails to differentiate self from foreign, the effector mechanisms are directed towards the individual s own tissues, and pathological autoimmune disease results. LÄS MER

  7. 25. Modulation of pain by immune factors : a study on interferon-g and its receptor in nociceptive transmission

    Författare :Kristina S Vikman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cytokines; interferon-gamma; dorsal horn; hypersensitivity; nociceptive transmission; pain; GluR1; AMPA receptor; disinhibition; spontaneous activity; primary cell culture; two-compartment model; spinal cord.;

    Sammanfattning : Immune cytokines have been implicated as important neuromodulators, contributing to neuronal plasticity both in the adult and developing nervous system. In addition, they have been assigned a potential role in the generation of pathological pain, which may occur as a severe symptom following disease states in the nervous system. LÄS MER