Sökning: "IFN-γ"

Visar resultat 11 - 15 av 203 avhandlingar innehållade ordet IFN-γ.

  1. 11. Immunological aspects of latent tuberculosis infection during pregnancy

    Författare :Fregenet Tesfaye Tegegn; Klinisk infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Interferon-γ; immune mediators; latent tuberculosis infection; Mtb-antigen reactivity; pregnancy; QuantiFERON-TB Gold Plus;

    Sammanfattning : Pregnancy-induced immune modulation might lead to reactivation of latent tuberculosis infection (LTBI). This thesis explores aspects of immune-based LTBI diagnostics and how pregnancy affects the immune control of Mycobacterium tuberculosis (Mtb) infection. We studied a prospective cohort of women recruited during pregnancy in Ethiopia. LÄS MER

  3. 12. Innate immunity to intracellular bacterial infections

    Författare :Christian Trumstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Intracellular bacterial pathogens have developed mechanisms to enter and invade cells, to survive the immune response and to replicate inside the host. We studied the innate mechanisms that have evolved in the host to battle intracellular bacterial pathogens, such as the obligate intracellular Chlamydia pneumoniae and the facultative intracellular Listeria monocytogenes, which invade the respiratory and the gastrointestinal tracts in humans. LÄS MER

  4. 13. Dissection of immunity controlling spread and growth of Listeria monocytogenes in neuronal cells

    Författare :Yuxuan Jin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :L. monocytogenes; nervous system; neuroinvasion; IFN-ã; CSF-1; neuron; NK cells; T cells; MHC;

    Sammanfattning : Listeria monocytogenes is a Grain-positive, facultative intracellular bacterium that causes severe infections in the nervous system of domestic animals and humans. Rhombencephalitis (brainstem encephalitis) due to L. monocytogenes, is a localized brainstem infection that is frequent in ruminants, and has been reported in humans as well. LÄS MER

  5. 14. Circulating Biomarkers in Patients with Head and Neck Cancer and the Influence of Cigarette Smoking

    Författare :Bengt-Åke Andersson; Nongnit Laytragoon-Lewin; Pierre Åman; Charlotta Dabrosin; Mikael Johansson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Head and neck cancer (HNC) is a collective name for heterogeneous tumors located in the head and neck regions for which smoking, alcohol and human papillomavirus (HPV) are documented risk factors. The survival of HNC patients has only improved marginally during the last decade. LÄS MER

  7. 15. Regulation of T cells in Atherosclerosis

    Författare :Megan Mulholland; Kardiovaskulär forskning - cellulär metabolism och inflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Atherosclerosis, the underlying pathology of cardiovascular diseases such as myocardial infarction and ischemic stroke, is characterized by chronic inflammation. T cells are present in atherosclerotic plaques and have been implicated in its pathogenesis. LÄS MER