Sökning: "ICL"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet ICL.
1. Interstrand Crosslinks - Induction and repair
Sammanfattning : DNA crosslinking agents exhibit a variety of DNA lesions, such as monoadducts, DNA-DNA interstrand or intrastrand crosslinks or DNA-protein crosslinks. Agents that produce interstrand crosslinks (ICLs) exist naturally and are widely used in chemotherapy. Therefore, it is important to understand how the lesions induced by these agents are repaired. LÄS MER
2. Heterogeneous Degradation and Recyclability of PP Studied by Imaging Chemiluminescence
Sammanfattning : Oxidative degradation is a serious threat to long-term use and recyclability of polymers. Successful recycling of polymeric quality products requires characterization of the polymer material after reprocessing and use. LÄS MER
3. Finding synergies for cancer treatment : new ways to modulate DNA damage repair by CX3CR1 and PFKFB3 inhibition
Sammanfattning : The goal of targeted cancer therapy is to selectively kill cancer cells based on their molecular survival mechanisms. DNA repair is as a promising cancer target as many cancers have chronic replication stress and deficiencies in the DNA damage response. LÄS MER
4. New Approaches to Investigate and Prevent Oxidation of Polypropylene
Sammanfattning : When employing chemiluminescence to evaluate stabiliserperformance in a polymer, the induction time or the time toreach maximum chemiluminescence intensity is often used. Insuch an experiment the longest part of the experiment isnormally the time before the oxidation starts. LÄS MER
5. Imaging chemiluminescence applied to oxidation of rubber materials and polyamide
Sammanfattning : In this thesis the heterogeneous nature of thermal oxidationof polymer materials have been investigated by imagingchemiluminescence (KL). The issues of oxidation depth profilesand physical spreading of oxidation in rubbers materials andpolyamide have been addressed. LÄS MER