Sökning: "Hypoxia"

Visar resultat 21 - 25 av 443 avhandlingar innehållade ordet Hypoxia.

  1. 21. Energy metabolic failure within the arterial wall in atherosclerosis

    Författare :Max Levin; Göteborgs universitet; []
    Nyckelord :atherosclerosis; hypoxia; hypoxia marker; bioluminescence imaging; ATP; glucose; lactate; energy metabolism;

    Sammanfattning : Atherosclerosis is a disease that affects large and medium sized arteries. The majority of deaths in a Western population can be directly attributed to complications of this disease. Although research efforts have been vast, the pathophysiological mechanisms underlying atherosclerosis are not fully understood. LÄS MER

  3. 22. Effects of arsenic trioxide and hypoxia in multidrug-resistant neuroblastoma

    Författare :Jenny Karlsson; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk biologi; Clinical biology; neuroblastoma; multidrug resistance; hypoxia; glucose-deficiency; cell death; Bax; Apoptosis; arsenic trioxide;

    Sammanfattning : Neuroblastoma is a childhood tumour derived from the sympathetic nervous system. Although most children with neuroblastoma initially respond to treatment, approximately 50% of these patients relapse with multidrug-resistant tumours. Arsenic trioxide (As2O3) has been used for centuries to treat different clinical disorders including malignancies. LÄS MER

  4. 23. Roles of Heparan Sulfate in Amyloid-β Pathology and Hypoxia

    Författare :Elina Hjertström; Jin-ping Li; Ulf Lindahl; Sally Stringer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparan sulfate; Alzheimer s disease; Aβ; Proteoglycan; Heparanase; Amyloid; Hypoxia; Cancer; Spalax; Biochemistry; Biokemi; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : Heparan sulfate (HS) is a highly sulfated polysaccharide expressed on the cell surface and in the extracellular matrix, interacting with a large number of proteins. HS is implicated in human diseases, including different types of cancer and amyloid diseases such as Alzheimer's disease (AD). LÄS MER

  5. 24. Biomarkers and bioindicators of hypoxia and sediment toxicity in Monoporeia affinis

    Författare :Marie Löf; Brita Sundelin; Tina Elfwing; Elena Gorokhova; Ingela Dahllöf; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biomarkers; Bioindicators; Embryo aberrations; Hypoxia; Contaminated sediment; PAHs; PCBs; Metals; Baltic Sea; Amphipods; Monoporeia affinis; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : Two of the most pressing environmental problems in the Baltic Sea are pollution and oxygen deficiency. The aim of this doctoral thesis was to evaluate a set of biomarkers and reproductive variables in the amphipod Monoporeia affinis to test their suitability as indicators of exposure to contaminants and hypoxia. LÄS MER

  7. 25. The venous circulation in teleost fish -responses to exercise, temperature and hypoxia

    Författare :Erik Sandblom; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; blood volume; catecholamines; central venous pressure; exercise; hypoxia; mean circulatory filling pressure; preload; renin-angiotensin; temperature; vascular capacitance.;

    Sammanfattning : Sandblom, Erik (2007). The venous circulation in teleost fish -Responses to exercise, temperature and hypoxia. Department of Zoology/Zoophysiology, Göteborg University, Box 463, SE-405 30 Göteborg, Sweden. In fish and other vertebrates, venous capacitance changes have important implications on venous return and cardiac filling pressure. LÄS MER