Sökning: "Hyperpolarized"
Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet Hyperpolarized.
1. Hyperpolarized Nuclei for NMR Imaging and Spectroscopy – Methodology and model studies of lung and vascular function
Sammanfattning : Based on the principle of nuclear magnetic resonance (NMR), magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) are widely used methods in medical diagnostic imaging and biological research. Clinical MRI has been restricted to imaging of protons, for reasons of sensitivity. LÄS MER
2. Contrast-Enhanced Magnetic Resonance Angiography - Development and optimization of techniques for paramagnetic and hyperpolarized contrast media
Sammanfattning : Contrast-enhanced magnetic resonance angiography (CE-MRA) is a diagnostic method for imaging of vascular structures based on nuclear magnetic resonance. Vascular enhancement is achieved by injection of a contrast medium (CM). LÄS MER
3. Hyperpolarized 3He-diffusion MRI in evaluation of lung structure in emphysema. Validation and development of the method
Sammanfattning : Abstract COPD is a major cause of chronic morbidity and mortality throughout the world. It is a preventable and treatable disease. Smoking is the most commonly encountered risk factor for COPD and the habit now unfortunately starts at earlier ages than before. LÄS MER
4. NMR Imaging of Flow and Perfusion using Hyperpolarized Nuclei: Theoretical Considerations and Application to Experimental Models
Sammanfattning : In the studies presented in this thesis, hyperpolarized tracers have been used for the study of macroscopic flow and capillary perfusion with magnetic resonance imaging. The feasibility of performing vascular studies using echo-planar imaging (EPI) and hyperpolarized 129Xe was investigated using xenon dissolved in ethanol prior to injection into a flow phantom. LÄS MER
5. Structure of the distal lung studied with inhaled nanoparticles
Sammanfattning : Techniques able to detect impairments in the distal human lung are lacking. Since inhaled nanoparticles are predominantly deposited in the acini, their deposition can be used to derive structural properties of the region. Intheory, structural enlargements in the distal lung imply that less inhaled nanoparticles deposit there. LÄS MER