Avancerad sökning
Hittade 4 avhandlingar som matchar ovanstående sökkriterier.
1. Improved techniques for CE-MALDI-MS off-line coupling and MALDI-MS analysis of primarily hydrophobic proteins and peptides
Sammanfattning : Due to the hydrophobic nature of integral membrane proteins (IMP) they give rise to several difficulties concerning handling and analysis, which is not the case for the most water soluble proteins. New analysis methods are needed, where the insolubility problems of the hydrophobic proteins due to aggregation and adhesion are tackled. LÄS MER
2. POLYPEPTIDES - STRUCTURES AND INTERACTIONS IN MONOLAYERS AND AQUEOUS SOLUTIONS
Sammanfattning : The aim of this thesis work is to understand and be able to control polypeptide conformation and interactions at interfaces and in solution by changing the solution conditions. For this purpose simple model polypeptides, so-called polyamino acids, have been investigated at the air-liquid interface, as well as in aqueous solutions. LÄS MER
3. Partitioning of biomolecules in thermoseparating polymer-water two-phase systems
Sammanfattning : The partitioning behaviour of different types of molecules in thermoseparating two-phase systems has been studied. A thermoseparating two phase system was formed by heating a water solution, which contained a thermoseparating polymer, above the cloud point temperature. LÄS MER
4. Targeting HER2-expressing tumors with potent drug conjugates and fusion toxins based on scaffold proteins
Sammanfattning : Targeted therapy is an emerging treatment for a variety of cancers. Small- sized scaffold proteins are an alternative to conventional antibody-based targeting molecules. LÄS MER