Sökning: "Human skeleton"

Visar resultat 6 - 10 av 39 avhandlingar innehållade orden Human skeleton.

  1. 6. Genetic and genomic analysis of arthritis regulating regions in human and mouse

    Författare :Lina Olsson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Immunologi; serologi; transplantation; Skeleton; muscle system; serology; Immunology; Medicin människa och djur ; Medicine human and vertebrates ; QTL; NADPH oxidase complex; Rheumatoid Arthritis; Genetic Analysis;

    Sammanfattning : Identifying genes involved in the disease pathways of complex diseases such as Rheumatoid arthritis (RA) has been shown to be very difficult. Despite decades of research still only a handful of genes have been convincingly identified as risk genes. LÄS MER

  3. 7. Identification and characterization of a novel cartilage gene product CILP, which is an early indicator of osteoarthritis

    Författare :Pilar Lorenzo; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; Skeleton; matrix protein; NTPPHase; CILP; osteoarthritis; human cartilage; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

    Sammanfattning : The aim of this work was to study alterations in the matrix composition of human articular cartilage in different stages of osteoarthritis and to isolate and characterize one of the proteins that is altered in the osteoarthritic process. The metabolism of articular cartilage in different stages of osteoarthritis including early asymptomatic OA was monitored in a culture system of metabolically labeled cartilage explants. LÄS MER

  4. 8. On the etiology and pathogenesis of systemic lupus erythematosus with special reference to environmental factors

    Författare :Anders Bengtsson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; Risk factors; Human parvovirus B19; Immune complex; Disease activity; Interferon-alpha; SLE; Retrovirus;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease in which environmental factors interact with genetic factors in the development of the disease process and evolution of clinical manifestations. In this thesis both exogenous factors and host factors were investigated, as well as important immunopathological aspects including involvement of immune complex (IC), the complement system and interferon-alpha (IFN-α). LÄS MER

  5. 9. Enhancing material and biological properties of calcium phosphate bone substitute

    Författare :Christopher Camire; Lund Ortopedi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; materialteknik; Non-metallic mineral technology; Icke-metallisk mineralteknik; Biotechnology; Bioteknik; Materiallära; Material technology; Technological sciences; Teknik; Naturvetenskap; reumatologi; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi; Natural science; muskelsystem; Skelett; muscle system; rheumatology locomotion; Bone Substitute; Calcium Phosphate; Skeleton; Medicin människa och djur ; Medicine human and vertebrates ; Osteoconductivity; Silicon; Mechanical Properties; Crystallinity; Reactivity; Calorimetry; Hydroxyapatite;

    Sammanfattning : Calcium phosphate materials (CaPs) have proven biocompatible and useful in clinical situations. One CaP showing promise in the clinic is alpha phase tricalcium phosphate ([alpha]-TCP). [alpha]-TCP in powder form can be hydrated and undergoes a reaction resulting in calcium deficient hydroxyapatite (CDHA). LÄS MER

  7. 10. Identification of Arthritis Susceptibility Genes in Mice and Humans

    Författare :Emma Ahlqvist; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; serology; Immunology; Medicin människa och djur ; Medicine human and vertebrates ; Biomedicinska vetenskaper; QTL; Biomedical sciences; Rheumatoid arthritis; Collagen-induced arthritis; serologi; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Clinical genetics; Klinisk genetik;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic autoimmune disease with a largely unknown aetiology. The risk of developing RA is partly dependent on genetic factors, which has motivated extensive efforts to identify the disease regulating genes as away to understand disease pathogenesis. LÄS MER