Sökning: "Human pluripotent stem cells"
Visar resultat 6 - 10 av 100 avhandlingar innehållade orden Human pluripotent stem cells.
6. Human Embryonic Stem Cells; A novel model system for early human development
Sammanfattning : Human embryonic stem cells (HESC) have since their first description in 1998 been recognized as a theoretically endless source of cells capable of differentiation into any somatic cell type. Although great attention has been given to their potential use in cell- based therapy, they are equally important as research tools for studies on early human development, both normal and diseased. LÄS MER
7. Modelling Human Developmental Hematopoiesis. Towards in vitro Generation of Human Hematopoietic Stem Cells
Sammanfattning : The possibility to manufacture hematopoietic stem cells (HSCs) in the laboratory would provide an indefinite source of cells for patients requiring bone marrow transplantation. Moreover, combined with the progress in gene editing techniques, it would provide a novel platform for gene and cell replacement therapies for a range of currently incurable congenic and acquired disorders. LÄS MER
8. Expression of Tissue Antigens in Human Pluripotent Stem Cells and Alterations During Differentiation : Potential application in regenerative medicine for treatment of terminal cell and organ failure
Sammanfattning : The major limiting factor in the treatment of patients with end-stage organ failure is the insufficient number of human organs available for transplantation. An unlimited access to human cells, tissues and organs would also open up possibilities to treat several chronic diseases, such as diabetes, neurological and cardiovascular diseases, affecting millions of patients worldwide. LÄS MER
9. Human induced pluripotent stem cells in regenerative medicine
Sammanfattning : Human induced pluripotent (iPS) cells offer a theoretically inexhaustible cell source for the derivation of any cell type and are a promising tool in regenerative medicine. Cells can be derived from the recipients own tissue or from pre-selected HLA-matched donors. LÄS MER
10. In vitro toxicity testing using human pluripotent stem cell derivatives
Sammanfattning : .... LÄS MER