Sökning: "Human pluripotent stem cells"

Visar resultat 16 - 20 av 100 avhandlingar innehållade orden Human pluripotent stem cells.

  1. 16. Pluripotent Circulations: Analyzing Articulations of Stem Cells in the USA, prior to 2001

    Författare :Morten Sager; Göteborgs universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Actor-Network Theory; meta-theory; obligatory point of passage; boundary objects; sociotechnical reality; articulations; human embryonic stem cells; spare embryos; pluripotency;

    Sammanfattning : In this thesis, stem cell research and politics in the USA are analyzed by using actor-network theory (ANT). Here ANT is put to work on largely textual materials, often directly from US political settings, such as Congressional debates and national panels. LÄS MER

  3. 17. Developing new models of childhood malignancies using human induced pluripotent stem cells

    Författare :Ana Marin Navarro; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Early onset diseases such as childhood malignancies and neurodevelopmental disorders have been intricate to study. For many years, research has relied and dependent upon different animal systems. LÄS MER

  4. 18. Exploring Direct Conversion of Human Glia into Therapeutic Neurons

    Författare :Jessica Giacomoni; Utvecklings- och regenerativ neurobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human embryonic stem cells; glial progenitor cells; neuronal reprogramming; induced neurons; spheroids; brain slice cultures; neurodegenerative disorders;

    Sammanfattning : Direct neuronal reprogramming of a somatic cell into therapeutic neurons, without a transient pluripotent state, provides new promise for the large number of individuals afflicted by neurodegenerative diseases or brain injury. This approach could be potentially applied directly in the brain by targeting resident cells as a source of new neurons. LÄS MER

  5. 19. Generation of human astrocytes for disease modeling. A study based on stem cells, direct conversion and genome engineering to dissect the role of astrocytes in leukodystrophies

    Författare :Ella Quist; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Astrocytes; Stem Cells; transcription factor programming; direct conversion; genome engineering; CRISPR Cas9; leukodystrophy;

    Sammanfattning : Astrocytes are one of the major cell types in the central nervous system and are indispensable for brain development and function. The human brain and human astrocytes have unique structures and functions that are not present in other animal species. LÄS MER

  7. 20. Stem Cell Plasticity Controlling Neuronal Differentiation Prior to Cell Transplantation

    Författare :Laurent Roybon; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Differentiation; Stem cells; Immunology; serology; Immunologi; serologi; transplantation;

    Sammanfattning : Parkinson's disease (PD) is the second most common neurodegenerative disease and affects 2% of the population over 65 years of age. The disease is characterized by the progressive loss of dopaminergic neurons. Over time, symptoms increase and, in particular, lead to a dramatic slowness of movements. LÄS MER