Sökning: "Human herpesvirus 6A"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Human herpesvirus 6A.

  1. 1. Environmental risk factors for the occurrence of multiple sclerosis

    Författare :Martin Biström; Peter Sundström; Johan Hultdin; Jonatan Salzer; Kjell-Morten Myhr; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple sclerosis; risk factors; epidemiology; case-control study; Human herpesvirus 6A; Human herpesvirus 6B; leptin; insulin; Epstein-Barr virus; vitamin D; Neurology; neurologi;

    Sammanfattning : Background. Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system that typically debuts around age 30. About 2.3 million people are affected in the world today, and besides trauma it is the most common cause of neurological disability among young adults in the western world. LÄS MER

  2. 2. Human herpesvirus 6A and 6B : assay validation, virus-host interaction and clinical relevance

    Författare :Elin Engdahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human herpesvirus (HHV)-6A and HHV-6B are two ubiquitous herpesviruses that after primary infection can stay latent in the host. The two viruses can reactivate from latency and cause secondary complications. Also, diseases like multiple sclerosis and epilepsy have been associated with HHV-6A and HHV-6B. LÄS MER

  3. 3. Differences i tropism and viral assembly pathways of human herpesvirus 6A and 6B (HHV-6A and 6B) and association of host cell proteins in HHV-6A virions

    Författare :Jenny Ahlqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human herpesvirus 6A and 6B (HHV-6A and 6B) are considered to be T-lymphotropic viruses. The overall nucleotide sequence identity between the two variants is 90% and each differs by only nine variant-specific open reading frames. HHV-6A and 6B have often been recognized as one virus and simply termed HHV-6. LÄS MER

  4. 4. Human herpesvirus-6 in multiple sclerosis : assay development, immune responses and host genetics

    Författare :Rasmus Gustafsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : MS is a chronic inflammatory demyelinating disease of the CNS that implies impaired motor- and cognitive functions. Life expectancy is not severely affected but the disease has substantial negative effects on the quality of life of patients and their relatives. LÄS MER

  5. 5. Molecular and diagnostic aspects of the protein p41 of HHV-6 and silencing of the CD46 receptor by RNA interference

    Författare :Yunhe Xu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Human herpesvirus 6; p41; multiple sclerosis; RNA interference; small interfering RNAs; CD46;

    Sammanfattning : Multiple sclerosis (MS) is one of the most common diseases of the central nervous system (CNS), leading to sensory and motor disability in young adults. There is no efficient treatment of the disease. Its etiology is unknown. LÄS MER