Sökning: "Human breast cancer cells"

Visar resultat 6 - 10 av 178 avhandlingar innehållade orden Human breast cancer cells.

  1. 6. Role of Wnt-5a in breast cancer

    Författare :Janna Sand-Dejmek; Malmö Experimentell patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; signal transduction; metastasis; adhesion; breast cancer; Syk; Wnt-5a; DDR1; pathological anatomy; Patologi allmän ; patologisk anatomi;

    Sammanfattning : Breast cancer is one of the most common cancer forms in the industrialized world. Only in Sweden, nearly 6000 women are diagnosed with breast cancer each year and 1/3 of them eventually succumb to the disease. LÄS MER

  3. 7. Human secretoglobins in normal and neoplastic cells and tissues

    Författare :Anna Sjödin; Håkan Hedman; Roger Henriksson; Mårten Fernö; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; secretoglobins; mammaglobin; lipophilin; breast cancer; pituitary; sweat gland; Onkologi; Oncology; Onkologi; onkologi; Oncology;

    Sammanfattning : Secretoglobins is a newly described polypeptide family that has gained a lot of interest in human cancer and inflammation research. Although the first secretoglobin polypeptide was discovered more than 30 years ago, their physiological function is still not known. LÄS MER

  4. 8. Growth factor signaling in the breast tumor microenvironment

    Författare :Matteo Bocci; Avdelningen för translationell cancerforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Tumor microenvironment; Angiogenesis; Cancer-associated fibroblasts; PDGF-C; ALK1;

    Sammanfattning : Cancer represents a collection of malignancies characterized by an aberrant expansion of cells. This unrestrained growth is the result of the acquisition of several pro-survival features and the evasion of cellular fail-safe mechanisms, collectively known as the hallmarks of cancer. LÄS MER

  5. 9. Regulation of Polyamine Analogue-Induced Apoptosis in Human Breast Cancer Cells

    Författare :Martina Holst; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cancer; Animal physiology; Djurfysiologi; Pharmacological sciences; pharmacognosy; pharmacy; onkologi; Cytologi; cancerology; oncology; Cytochrome c; Cytology; Bcl-2; Mitochondrial respiration; Apoptosis; Human breast cancer cells; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi; Social medicine; Socialmedicin; samhällsmedicin; Mitochondria; Polyamine analogues;

    Sammanfattning : Apoptosis is a defined process for cells to commit suicide through a set of biochemical and morphological cell changes. Activated apoptotic signals converge on the mitochondria, leading to permeabilization of mitochondrial membranes and release of different apoptosis regulatory proteins into the cytosol. LÄS MER

  7. 10. Translational Aspects of Erythropoietin Receptor and Hypoxia-Inducible Factors in Breast Cancer

    Författare :Anna-Maria Larsson; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast Cancer; Anemia; Hypoxia; Erythropoietin EPO ; EPO receptor EPOR ; Estrogen Receptor ER ; Hypoxia-Inducible Factors HIFs ; Tamoxifen Response; Proliferation;

    Sammanfattning : The main function of erythropoietin (EPO) is in hematopoiesis where EPO stimulates increased proliferation, survival and differentiation of erythrocytic precursors in response to hypoxia. The EPO effect is mediated via binding to the EPO receptor (EPOR), which induces activation of different intracellular signaling pathways. LÄS MER