Sökning: "Human alkaline phosphatase"

Visar resultat 11 - 15 av 21 avhandlingar innehållade orden Human alkaline phosphatase.

  1. 11. Biodegradable gelatin microcarriers in tissue engineering : In vitro studies on cartilage and bone

    Författare :Sofia Pettersson; Gunnar Kratz; Pentti Tengvall; Jonas Wetterö; Julie Gold; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Tissue engineering is a multidisciplinary field that combines cells, biomaterial scaffolds and environmental factors to achieve functional tissue repair. This thesis focuses on the use of macroporous gelatin microcarriers as scaffolds in tissue engineering applications, with a special focus on cartilage and bone formation by human adult cells in vitro. LÄS MER

  3. 12. Factors affecting growth, differentiation and apoptosis of osteoblastic and osteosarcoma cells

    Författare :Yan Li; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Osteoblasts play a fundamental role in determining bone structure and function. These cells originate from mesenchymal stem cells (MSCs) and through proliferation and differentiation develop into preosteoblasts and then into mature cells. LÄS MER

  4. 13. Cat allergy : diagnosis and characterization of important allergens

    Författare :Justus Adédoyin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Allergy affects about 25% of the population. Allergic diseases are manifested in many ways, from mild rhinitis to life-threatening anaphylaxis. Globally, more than 15% of children and adults are allergic to pets. The focus of this thesis is important cat allergens. LÄS MER

  5. 14. Evaluation of Functionalized Biopolymers as a Step Toward Targeted Therapy of Osteoporosis

    Författare :Sujit Kootala; Jöns Hilborn; Peter Thomsen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Osteoporosis; Bone regeneration; Biomaterials; Hyaluronic acid; Bisphosphonates; Osteoclasts; Osteoblasts; Growth factors; Kemi med inriktning mot polymerkemi; Chemistry with specialization in Polymer Chemistry; Kemi med inriktning mot materialkemi; Chemistry with specialization in Materials Chemistry;

    Sammanfattning : The work presented in this thesis focuses on the development of strategies and smart bioactive materials for the treatment of osteoporosis. High and low molecular weight soluble hyaluronic acid-bisphosphonate (HA-BP) derivatives were investigated for their ability to inhibit osteoclasts. LÄS MER

  7. 15. On osseointegration in response to controlled surface nanotopography

    Författare :Dimitrios Karazisis; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; in vivo; nanotopography; osseointegration; topography;

    Sammanfattning : Knowledge about the biological responses provoked by the surface modification of titanium implants on the nanoscale is still in its infancy. Although in vitro studies claim superior effects considering higher adhesion and proliferation of osteoblasts in the short term and even differentiation towards the osteogenic cell lineage in the long term, these responses do not necessarily reflect the actual outcome in the complex in vivo environment. LÄS MER