Sökning: "Human Immunodeficiency Virus"

Visar resultat 1 - 5 av 131 avhandlingar innehållade orden Human Immunodeficiency Virus.

  1. 1. Combination chemotherapy for human immunodeficiency virus infection

    Författare :Sarah Palmer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The worldwide spread of human immunodeficiency virus (HIV) has spurred the search for effective drugs to combat this deadly virus. The limited effect of monotherapy treatment, in large measure due to the development of drug resistant viral strains, has led to increased emphasis on combination chemotherapy for the treatment of HIV, the focus of this study. LÄS MER

  3. 2. Synthesis of inhibitors against the human immunodeficiency virus : diol-based inhibitors of the HIV-1 protase and 4-substituted carbocyclic nucleoside analogues

    Författare :Anna Mühlman; David Tanner; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Sammanfattning : The pandemic spread of HIV infection and AIDS has resulted in intensive research designed to develop effective therapeutic agents. Development of inexpensive inhibitors is necessary to allow treatment of HIV infections in the Third World.In the present thesis, the design and synthesis of several inhibitors of the HIV-1 virus are described. LÄS MER

  4. 3. Understanding Complex Diseases and Disease Causative Agents : The Machine Learning way

    Författare :Zeeshan Khaliq; Jan Komorowski; Steven Bosinger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Pathogens; Influenza A viruses; Human immunodeficiency virus; Simian immunodeficiency virus; Pathogenicity; Cancer; long noncoding RNAs; Machine learning; Host specificity; Host-specific signatures; Bioinformatics; Bioinformatik;

    Sammanfattning : Diseases can be caused by foreign agents – pathogens – such as viruses, bacteria and other parasites, entering the body or by an internal malfunction of the body itself. The partial understanding of diseases like cancer and the ones caused by viruses, like the influenza A viruses (IAVs) and the human immunodeficiency virus, means we still do not have an efficient cure or defence against them. LÄS MER

  5. 4. The battleground of two Infections and a cancer: Human Papilloma Virus, premalignant lesions of the cervix and their interaction with Human Immunodeficiency Virus in southwestern Nigeria

    Författare :Oliver Ezechi; Socialmedicin och global hälsa; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antiretroviral drugs; Human papilloma virus; cervical cancer; HIV AIDS; pre-cancerous lesions; Nigeria;

    Sammanfattning : Background: The highest numbers of HIV-infected women are in sub- Saharan Africa, where the natural progression of HIV disease in the absence of treatment results in death before the onset of invasive cervical cancer. With improved access to treatment, several studies outside West Africa demonstrated an increased risk of pre-invasive cervical lesions among HIV-infected women and the positive impact of treatment on the outcome. LÄS MER

  7. 5. Human immunodeficiency virus (HIV), human papillomavirus (HPV) and cervical cancer prevention in Uganda : prevalence, risk factors, benefits and challenges of post-exposure profylaxis, screening integration and vaccination

    Författare :Edward Kumakech; Sören Andersson; Vanja Berggren; Henry Wabinga; Asli Kulane; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV; HPV; Cervical cancer; Prevention; Post-exposure prophylaxis; screening integration; vaccination; Uganda; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : .... LÄS MER