Sökning: "Human Adipocytes"
Visar resultat 21 - 25 av 112 avhandlingar innehållade orden Human Adipocytes.
21. Human Dermal Fibroblasts in Tissue Engineering
Sammanfattning : The loss or failure of tissues and/or organs is one of the most frequent problems in modern healthcare. The field of tissue engineering applies the principles of biology and engineering in order to develop functional substitutes for damaged tissues. LÄS MER
22. Regulation of glycerol efflux in adipocytes. Structural and functional studies of the glycerol channel aquaporin 7
Sammanfattning : Glycerol levels in adipocytes depend on the lipolysis, the hydrolysis of triglycerides into glycerol and free fatty acids, and the efflux of glycerol across the plasma membrane through glycerol channels. The aims of this work were to investigate how glycerol levels are regulated on a molecular level by PLIN1, a major lipid droplet-associated protein and a key regulator of the lipolysis by scaffolding for lipolytic proteins on the lipid droplet. LÄS MER
23. Lipid Metabolism and Insulin Signalling in Adipocytes : enhanced autophagy in type 2 diabetes
Sammanfattning : Energy storage in the adipose tissue, to an extent leading to obesity, is associated with local as well assystemic insulin resistance. When insulin-producing beta-cells in the pancreas gradually fail tocompensate, plasma levels of glucose rise and overt type 2 diabetes is diagnosed. LÄS MER
24. Human adipose tissue. Genes predominantly expressed in the visceral depot and in hypertrophic adipocytes
Sammanfattning : The obesity prevalence is increasing worldwide and obesity is closely linked to type 2 diabetes and cardiovascular disease. Both visceral fat accumulation and enlarged adipocyte size are risk factors for obesity related metabolic disorders. LÄS MER
25. The regulatory role of microRNA in human adipocytes and their link to insulin resistance
Sammanfattning : White adipose tissue (WAT) is a highly plastic organ which secretes a large number of peptide factors termed adipokines. Increased caloric intake increases WAT mass which results in marked alterations in the secretory pattern. This may be mediated via both transcriptional and post-transcriptional mechanisms. LÄS MER