Sökning: "Hox genes"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden Hox genes.

  1. 1. Hox transcription factors in hematopoiesis

    Författare :Jon Mar Björnsson; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; extracellulära vätskor; Haematology; hematopoies; tet; Hox; cre lox;

    Sammanfattning : Hematopoiesis is a lifelong, dynamic process in which a small number of pluripotent hematopoietic stem cells (HSC) residing in the bone marrow (BM) give rise to billions of mature blood cells of both myeloid and lymphoid origin each day. This enormous capacity of HSC has been utilized in BM transplantations for 4 decades and is also very important for future gene therapy. LÄS MER

  2. 2. Analysis of Wnt ligands and Fz receptors in Ecdysozoa : Investigating the evolution of segmentation

    Författare :Mattias Hogvall; Ralf Janssen; Graham Budd; Andreas Hejnol; Javier Ortega-Hernández; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Segmentation; Onychophora; Wnt genes; Frizzled; Hox genes; Priapulida; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Sammanfattning : .... LÄS MER

  3. 3. Investigation of Hox gene expression and Wnt-signalling in basally branching ecdysozoans

    Författare :Mattias Hogvall; Ralf Janssen; Graham Budd; Andreas Hejnol; Andrew Peel; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Wnt signalling pathway; Hox genes; Fz receptors; Onychophora; Priapulida; Ecdysozoa; Biology with specialization in Evolutionary Organismal Biology; Biologi med inriktning mot evolutionär organismbiologi;

    Sammanfattning : One of the most important processes in the development of an animal is the determination and patterning of the primary body axis, the anterior-posterior (AP) axis. After the AP axis has been established the embryo grows and elongates through posterior elongation. LÄS MER

  4. 4. The Role of Hox Transcription Factors in the Regulation of Hematopoiesis

    Författare :Mattias Magnusson; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; extracellular fluids; Haematology; Hox genes; Knockout; Hematopoietic stem cells; Hematopoiesis; Transcription Factor;

    Sammanfattning : Hematopoiesis is a lifelong, dynamic process, originating from a low number of hematopoietic stem cells (HSCs) residing in the adult bone marrow with the ability to self-renew and generate all blood lineages throughout life. Recent findings have demonstrated that the Homeobox (Hox) transcription factors are important regulators of both normal and malignant hematopoiesis, controlling proliferation, differentiation and self-renewal of hematopoietic cells at different levels of the hematopoietic hierarchy. LÄS MER

  5. 5. Evolution of the Neuropeptide Y and Opioid Systems and their Genomic Regions

    Författare :Görel Sundström; Dan Larhammar; Manfred Schartl; Uppsala universitet; []
    Nyckelord :neuropeptide Y; opioid; evolution; genome duplication; gene duplication; Hox; SCN; IGFBP; MEDICINE; MEDICIN;

    Sammanfattning : Two whole genome duplications (2R) occurred early in vertebrate evolution. By using combined information from phylogenetic analyses and chromosomal location of genes, this thesis delineates the evolutionary history of two receptor-ligand systems that expanded by these large scale events. LÄS MER