Sökning: "Host-pathogen interactions"

Visar resultat 21 - 25 av 49 avhandlingar innehållade orden Host-pathogen interactions.

1. 21. It Takes Two to Tango : Bacterial heterogeneity and host cell features govern Salmonella infection

   Författare :Viktor Ek; Mikael E. Sellin; Francisco García del Portillo; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Salmonella; swimming; swim pattern; targetting; virulence; invasion; host-pathogen interactions; epithelium; epithelial cells; macrophages; monocytes; monolayer; flagella; genome; genetic; barcoding; discreet-invasion; shape; morphology; antibiotics; persistence; Mikrobiologi; Microbiology;

   Sammanfattning : Salmonella enterica serovar Typhimurium (S.Tm) causes enterocolitis with significant worldwide morbidity and mortality. The general aim of this thesis is to investigate variation in host cell invasion mechanisms used by S.Tm across different host cell contexts, as well as the influence of bacterial cell-cell heterogeneity on invasion-relevant S. LÄS MER

3. 22. Eco-immunological studies of innate immunity in Mallards (Anas platyrhynchos)

   Författare :Anu S. Helin; Jonas Waldenström; Edwin Veldhuizen; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Avian β-defensins AvBDs ; Avian gene expression; Host-pathogen interactions; Innate immunity; Mallard Anas platyrhynchos ; Myxovirus resistance gene Mx ; Retinoic acid inducible gene 1 RIG-I ; Avian β-defensins AvBD ; Genuttryck; Gräsand Anas platyrhynchos ; Immunförsvar; Immungener; Myxovirus resistant gene Mx ; Patogen; Retinoic acid inducible gene 1 RIG-I ; Ecology; Ekologi;

   Sammanfattning : This thesis comprises two sections, both of which explore eco-immunology of the innate immune system of mallards (Anas platyrhynchos). The innate immune system serves a pivotal role as the first line of defense against invading pathogens, and is comprised of physical and chemical barriers. LÄS MER

4. 23. Biology of a small RNA virus that infects Drosophila melanogaster

   Författare :Sajna Anand Sadanandan; Dan Hultmark; Francis Jiggins; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nora virus; Drosophila melanogaster; virus biology; host-pathogen interaction; molekylärbiologi; Molecular Biology;

   Sammanfattning : Drosophila melanogaster has been extensively used as a model organism to study diverse facets of biology, including host-pathogen interactions and the basic biology of its pathogens. I have used the fruit fly as a model to study elementary aspects of Nora virus biology, such as the role of the different proteins encoded by the virus genome. LÄS MER

5. 24. All Roads Lead to the Non-Coding RNome : Evolution of Multicellularity and Host Response to Bacterial Infection

   Författare :Jonas Kjellin; Fredrik Söderbom; Jonathan Chubb; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ncRNA; Dictyostelia; miRNA; Class I RNA; host-pathogen interaction; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Sammanfattning : The ability to control gene expression is fundamental for all living organisms. Therefore, a large variety of regulatory mechanisms exist in each cell which are essential for e.g. developmental processes and to quickly adapt to different cellular stresses such as infection. LÄS MER

7. 25. Regulatory networks of c-di-GMP signalling involved in biofilm formation, motility and host pathogen interactions in Salmonella typhimurium

   Författare :Irfan Ahmad; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Adaptation to altered environmental conditions is one of the fundamental bacterial characteristics. The ubiquitous second messenger c-di-GMP plays a key role to adopt bacterial behaviour. Transition from motility to sessility and from acute infection to chronic infection is regulated by c-di-GMP signalling in many bacteria. LÄS MER