Sökning: "Host-pathogen interaction"

Visar resultat 11 - 15 av 33 avhandlingar innehållade orden Host-pathogen interaction.

  1. 11. All Roads Lead to the Non-Coding RNome : Evolution of Multicellularity and Host Response to Bacterial Infection

    Författare :Jonas Kjellin; Fredrik Söderbom; Jonathan Chubb; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ncRNA; Dictyostelia; miRNA; Class I RNA; host-pathogen interaction; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : The ability to control gene expression is fundamental for all living organisms. Therefore, a large variety of regulatory mechanisms exist in each cell which are essential for e.g. developmental processes and to quickly adapt to different cellular stresses such as infection. LÄS MER

  3. 12. Role of POU/Oct transcription factors in Drosophila immunity

    Författare :Widad Dantoft; Ylva Engström; Anne Uv; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial peptides; Drosophila; host-pathogen interaction; immune gene expression; immune signaling; NF-kB; microbiota; POU Oct transcription factors; protein degradation; stress response; transcriptional regulation; Molecular Biology; molekylärbiologi;

    Sammanfattning : In response to infection, Drosophila melanogaster relies on the ability to mount a robust and potent innate immune response, characterized by induction of cellular and humoral processes. While rapid immune induction is of utmost importance, it is equally important to restrict and repress immune gene expression, where and when it is not needed. LÄS MER

  4. 13. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    Författare :Johanna Raffetseder; Maria Lerm; Olle Stendahl; Vesa Loitto; Trude Helen Flo; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Sammanfattning : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. LÄS MER

  5. 14. Caenorhabditis elegans as a model to elucidate host-pathogen interactions for human bacterial pathogens

    Författare :Xiao Hui Sem; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The soil nematode Caenorhabditis elegans is a popular host utilized to model bacterial virulence and microbial pathogenesis in vivo. This thesis explores the use of C. elegans for the study of host-pathogen interactions for two Gram-negative bacteria, Burkholderia thailandensis and Salmonella enterica. LÄS MER

  7. 15. Proteome-wide analysis of severe bacterial infections. The battle between host and pathogen

    Författare :Anahita Bakochi; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; Mass Spectrometry; Systems biology; Host adaptation; Meningitis; Streptococcus pneumoniae;

    Sammanfattning : The pathogenesis of severe infectious diseases is a complex interplay between the host and the pathogen. The development and progression of a disease encompasses a multitude of processes, which balance between host-damage and host-protection. LÄS MER