Sökning: "Hong Xu"

Hittade 2 avhandlingar innehållade orden Hong Xu.

1. 1. Diet, lifestyle and chronic kidney disease

   Författare :Hong Xu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Chronic kidney disease (CKD) is a rapidly growing public health problem, affecting 5-10% of the general population, and individuals with CKD have a substantially increased risk of morbi-mortality. Early detection and treatment can delay or prevent onset many of the adverse outcomes of CKD. LÄS MER

3. 2. The role of TPPII in apoptosis control and treatment of malignant disease

   Författare :Hong Xu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :proteasome; tripeptidyl peptidase II; apoptosis; inhibitor of apoptosis LAP ; p53; Phosphoinositid-30H-kinase-related-kinases PIKK ;

   Sammanfattning : Degradation of cytosolic proteins depends largely on the proteasome. This complex contains a catalytic core (20S) and an accessory complex (19S) that recognizes ubiquitinated substrates and translocates these to the catalytic sites in the 20S particle. LÄS MER