Sökning: "Hong Jiao"

Hittade 1 avhandling innehållade orden Hong Jiao.

1. 1. Genetic dissection of multifactorial disease models in the rat

   Författare :Hong Jiao; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Type 2 daibetes; Goto-Kakizaki rat; linkage analysis; quantitative trait locus; gene-gene interaction; mitochondrial sequence; parent-of-origin;

   Sammanfattning : Type 2 diabetes (T2D) is characterized by two apparently distinct pathophysiologic defects - insulin resistance and a failure of the pancreatic Beta-cells to compensate for this resistance by appropriately increasing insulin secretion. There is strong evidence for an important role of genetics in both of these components. LÄS MER