Sökning: "Homeobox gene"
Visar resultat 1 - 5 av 28 avhandlingar innehållade orden Homeobox gene.
1. The Role of the Homeobox Gene ATHB16 in Development Regulation in Arabidopsis thaliana
Sammanfattning : There are 42 members of the homeodomain-leucine zipper (HDZip) family of transcription factors in Arabidopsis thaliana. This thesis focuses on the functional analysis of one member of this family, ATHB16, and on the biochemical properties of HDZip proteins. LÄS MER
2. The Role of HoxB4 in Hematopoiesis
Sammanfattning : HOXB4 is one of 39 members of the homeobox (HOX) family, a family of transcription factors involved in embryonic development. Several HOX transcription factors, including HOXB4, are highly expressed in hematopoietic stem cells (HSCs) but are downregulated upon differentiation towards more mature progeny cells. LÄS MER
3. Homeobox B13 in breast cancer : Prediction of tamoxifen benefit
Sammanfattning : A major issue in the management of breast cancer is to identify patients who are less likely to be cured after primary treatment and would benefit from adjuvant chemotherapy. Of great importance is also identification of patients with only local disease who traditionally would be given chemotherapy but would survive without. LÄS MER
4. The Role of Lhx2 During Organogenesis : - Analysis of the Hepatic, Hematopoietic and Olfactory Systems
Sammanfattning : During embryonic development a variety of tissues and organs such as the lung, eye, and kidney are being formed. The generation of functional organs is regulated by reciprocal cell-cell interactions. Via the secretion of soluble molecules one type of cells affect the fate of their neighboring cells. LÄS MER
5. Biological signature of HER2-positive breast cancer
Sammanfattning : Human epidermal growth factor receptor 2 (HER2) overexpressing breast cancers (HER2+ breast cancer) are associated with an aggressive disease course. This thesis is focused on improving the understanding of the biological signature of HER2+ breast cancer. LÄS MER