Sökning: "Hodgkin’s lymphoma"

Visar resultat 16 - 20 av 48 avhandlingar innehållade orden Hodgkin’s lymphoma.

1. 16. Transcriptional regulation of the Epstein-Barr virus nuclear antigen 1 gene in latent and lytic stages of infection

   Författare :Henrik Zetterberg; Göteborgs universitet; []
   Nyckelord :Epstein-Barr virus; EBNA1; Burkitt s lymphoma; nasopharyngeal carcinoma; ; B-lymphocyte; transformation; transcriptional regulation;

   Sammanfattning : Epstein-Barr virus (EBV) is a lymphotropic herpesvirus that infects more than 90% of humans worldwide. The virus is the causative agent of infectious mononucleosis, a self-limiting lymphoproliferative disorder, and is also associated with a variety of malignancies including Burkitt's lymphoma (BL), Hodgkin's disease (HD), nasopharyngeal carcinoma (NPC), and lymphoproliferative disorders in immunocompromised individuals. LÄS MER

3. 17. Clinical and immunopathological studies in Hodgkin's disease with special reference to prognosis

   Författare :Ulla Axdorph; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Hodgkin's disease (HD) and non-Hodgkin lymphoma (NHL) have certain features in common, but also distinct clinical and pathological differences. Thus, HD has many features of both an infectious (fever, leukocytosis, eosinophilia, night sweats, lymphadenopathy, splenomegaly) and a malignant process with few tumour cells, T-cell accumulation and sclerosis. LÄS MER

4. 18. Living and Dying with Primary Sjögren's Syndrome Studies on Aetiology, Treatment, Lymphoma, Survival and Predictors

   Författare :Elke Theander; Internmedicin - epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skeleton; transplantation; muskelsystem; Skelett; rheumatology locomotion; long-term outcome; Sjögren s Syndrome; Helicobacter pylori infection; prospective cohort studies; SMR; SIR for lymphoproliferative disease; fatigue; health-related quality of life; complement function; oncology; Cytologi; Immunology; cancer; serologi; Immunologi; serology; cancerology; onkologi; reumatologi; muscle system; CD4 T-lymphocytopenia; Cytology;

   Sammanfattning : This work was aimed at improving our understanding of the course of primary Sjögren's syndrome (SS). The Malmö SS patient register and the 2002 American-European Consensus Criteria formed the basis of all studies. Helicobacter pylori (H. LÄS MER

5. 19. Standardization and application of quantitative PCR methods in patients with hematological malignancies

   Författare :Maria Malec; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Polymerase chain reaction; RQ-PCR; Minimal Residual Disease; Acute leukemia; Hodgkin s Lymphoma; cytokines;

   Sammanfattning : Using modem combination chemotherapy regimens, it has been possible to increase the rate of complete remission (CR) in acute lymphoblastic (ALL) and acute myeloid leukemia (AML). The major reason for treatment failure in acute leukemia (AL) is the resistance of leukemic blasts to chemotherapeutic agents, which is accompanied by an inability of the immune system to eradicate residual leukemic cells surviving initial treatment. LÄS MER

7. 20. Targeted CD52 therapy in lymphoid malignancies : a clinical and immunological study

   Författare :Jeanette Lundin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :CD52; alemtuzumab; Campath; monoclonal antibodies; chronic lymphocytic leukemia; non-Hodgkin s lymphoma; mycosis fungoides; immune suppression;

   Sammanfattning : There is a great need for developing new treatment alternatives in low grade non Hodgkin's lymphoma (NHL) including chronic lymphocytic leukemia (CLL). The CD52 antigen, which is expressed on almost all lymphoid malignancies, can be utilized as a target for CD52-directed monoclonal antibody therapy (alemtuzumab, Campath-1 H). LÄS MER