Sökning: "Hober Didier"

Hittade 2 avhandlingar innehållade orden Hober Didier.

1. 1. Studies of Enterovirus Infection and Induction of Innate Immunity in Human Pancreatic Cells

   Författare :Mahesh Anagandula; Magnus Essand; Didier Hober; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; Enterovirus; Innate Immunity; Pancreas;

   Sammanfattning : Several epidemiological and clinical studies have indicated a possible role of Enterovirus (EV) infection in type 1 diabetes (T1D) development. However, the exact casual mechanism of these viruses in T1D development is not known. LÄS MER

3. 2. Enterovirus Implications in Type 1 Diabetes

   Författare :Monika Hodik; Hober didier; Uppsala universitet; []
   Nyckelord :Enterovirus; Coxsackie B virus; Type 1 diabetes; Pancreatitis;

   Sammanfattning : Human enteroviruses (HEVs), particularly Coxsackie B viruses (CVBs), might trigger the onset of type 1 diabetes (T1D), either by direct infection of the insulin-producing beta-cells or by an indirect inflammatory response. The overall aim of this thesis was to study the tropism of HEVs in isolated human pancreatic cell clusters in vitro including virus effects on islet function, gene-expression and ultrastructure. LÄS MER