Sökning: "Hjalmar Brismar"

Visar resultat 16 - 20 av 23 avhandlingar innehållade orden Hjalmar Brismar.

  1. 16. Approaches to Optimizing High Content Confocal Microscopy

    Författare :Erland Lewin; Hjalmar Brismar; Kjell S. Carlsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis presents two methods for improving high contentconfocal microscopy.The author's part in the first, "Toward a confocal subcellular atlasof the human proteome" was automating image capture of foursimultaneously tagged structures in cells in 96 well plates. In total,thousands of images of hundreds of proteins in cells. LÄS MER

  3. 17. Studies on the Role of Apoptosis in Kidney Diseases

    Författare :Linnéa Nilsson; Hjalmar Brismar; Anita Aperia; Lena Scott; Fredrik Palm; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Apoptosis; diabetic kidney disease; hyperglycemia; mesangial cells; microscopy; ouabain; podocytes; proximal tubule cells; RNA-seq; SGLT; Apoptos; diabetisk njursjukdom; hyperglykemi; mesangiala celler; mikroskopi; ouabain; podocyter; proximala tubuli celler; RNA-seq; SGLT; Biological Physics; Biologisk fysik;

    Sammanfattning : Apoptosis is one of the most common types of cell death. Under physiological conditions, it plays an essential role in removal of damaged and potentially harmful cells. Excessive apoptosis has however been linked to a number of diseases including proteinuric kidney disease and DKD, and is believed to enhance the disease progression. LÄS MER

  4. 18. Asymmetric Cellular Microenvironments

    Författare :Susanna Rydholm; Hjalmar Brismar; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; Fysik;

    Sammanfattning : This thesis presents methods to combine 3D cell culture, microfluidics and gradients on a controlled cellular scale. 3D cultures in biological extracellular matrix gels or synthetic gels bridge the gap between organ-tissue cultures and traditional 2D cultures. LÄS MER

  5. 19. Studies of Cellular Responses to External Stimuli in Engineered Microenvironments

    Författare :Susanna Rydholm; Hjalmar Brismar; Helle A. Praetorius; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; Fysik;

    Sammanfattning : .... LÄS MER

  7. 20. Dynamics of Enzymes at Interfaces : Lipase adsorption and mobility on solid surfaces

    Författare :Andreas Sonesson; Hjalmar Brismar; Robert Tilton; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biophysics; surface chemistry; diffusion; enzymes; lipases; adsorption; mobility; Physics; Fysik;

    Sammanfattning : This thesis aimed to give more insight in the dynamics of enzymes at interfaces. The adsorption and mobility of adsorbed proteins can e.g. give a better understanding of structure-function properties of interfacially active enzymes. LÄS MER