Sökning: "Hjalmar Brismar"

Visar resultat 11 - 15 av 23 avhandlingar innehållade orden Hjalmar Brismar.

  1. 11. Modeling Biophysical Mechanisms underlying Cellular Homeostasis

    Författare :Padideh Kamali-Zare; Hjalmar Brismar; Charles Nicholson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biological physics; Biologisk fysik;

    Sammanfattning : Cellular homeostasis is the effort of all living cells to maintain their intracellular content when facing physiological change(s) in the extracellular environment. To date, cellular homeostasis is known to be regulated mainly by time-consuming active mechanisms and via multiple signaling pathways within the cells. LÄS MER

  3. 12. Development of a covalent site-specific antibody labeling strategy by the use of photoactivable Z domains

    Författare :Anna Konrad; Sophia Hober; Hjalmar Brismar; Patrik Samuelsson; KTH; []
    Nyckelord :antibody labeling; site-specific; covalent; SPPS; Z domain; BPA; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : The joining of two molecular functions or the strategy of adding functions to proteins has been tremendously important for the development of proteins as tools in research and clinic. Depending on the intended application, there are a wide variety of functions that can be added to a proteins. LÄS MER

  4. 13. Mathematical Models in Cellular Biophysics

    Författare :Jacob Kowalewski; Hjalmar Brismar; Erik Fransén; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Calcium oscillations; Diffusion; Dopamine receptors; Mathematical models; Computer simulations; FRAP; Physics; Fysik;

    Sammanfattning : Cellular biophysics deals with, among other things, transport processes within cells. This thesis presents two studies where mathematical models have been used to explain how two of these processes occur. Cellular membranes separate cells from their exterior environment and also divide a cell into several subcellular regions. LÄS MER

  5. 14. Modeling and Data Analysis in Cellular Biophysics

    Författare :Jacob Kowalewski; Hjalmar Brismar; Anita Aperia; Björn Önfelt; Karl-Eric Magnusson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; Biofysik;

    Sammanfattning : Cellular biophysics deals with the physical aspects of cell biology. This thesis presents a number of studies where mathematical models and data analysis can increase our understanding of this field. LÄS MER

  7. 15. Studies on molecular mechanisms in calcium signaling and cellular energy consumption

    Författare :Kalaiselvan Krishnan; Hjalmar Brismar; Anders Tengholm; KTH; []
    Nyckelord :ca2 signaling; ATP; PercevalHR; NKA; diabetes; Angiotensin; Biological Physics; Biologisk fysik;

    Sammanfattning : Ion signaling plays fundamental role in cell survival. Na+ and Ca2+ are critical players in ion signaling. Cells spend the major amount of energy to maintain and regulate Na+ and Ca2+ gradients across the cell membrane. Any disruption in cellular energy consumption by plasma membrane ATPases affects ion signaling and vice versa. LÄS MER