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Visar resultat 6 - 10 av 73 avhandlingar som matchar ovanstående sökkriterier.

  1. 6. Development and Validation of HPLC Methods for Analytical and Preparative Purposes

    Författare :Johan Lindholm; Torgny Fornstedt; Karin Caldwell; Karl-Gustaf Wahlund; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; High performance liquid chromatography HPLC ; Analytical biotechnology; Sample preparation; Diode-array-detection DAD ; Mass spectrometry MS ; Validation; Preparative chromatography; Competitive isotherm parameters; Perturbation peak PP method; Kemi; Chemistry; Kemi;

    Sammanfattning : This thesis concerns the development and validation of high performance liquid chromatography (HPLC) methods aimed for two industrially important areas: (i) analysis of biotechnological synthesis and (ii) determination of adsorption isotherm parameters. There is today a lack of detailed recommendations for analytical procedures in the field of biotechnological production of drugs. LÄS MER

  2. 7. New approaches to preparation of macroporous monoliths for use in liquid chromatography

    Författare :Anh Mai Nguyen; Knut Irgum; Tatiana B. Tennikova; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; monolith; polycondensation; dissolution-precipitation; epoxy-amine; poly-amide; nylon; emulsion polymerization; characterization; protein separation; liquid chromatography; Analytical chemistry; Analytisk kemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : High performance liquid chromatography (HPLC) is one of the major techniques in separat-ion sciences. Faster separation and higher efficiency are required to meet ever-growing demands. Despite numerous studies and achievements on improving mass transfer in particulate packings discontinuity seems to be the cornerstone drawback in their development. LÄS MER

  3. 8. Miniaturized fluid system for high-pressure analytics

    Författare :Simon Södergren; Klas Hjort; Sami Franssila; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; High-pressure; Microfluidics; Thermal regulation; Fluid mechanics; In-situ sensors; High-pressure analytics; Teknisk fysik med inriktning mot mikrosystemteknik; Engineering Science with specialization in Microsystems Technology;

    Sammanfattning : High-pressure chemistry can be used to determine the contents of blood or water samples and to discover new chemistries. However, working with chemistry at pressures of many tens, or even hundreds, of bars often requires expensive and stationary equipment, such as autoclaves or chromatographic systems like high-performance liquid chromatography (HPLC). LÄS MER

  4. 9. Aspects of Optimisation of Separation of Drugs by Chemometrics

    Författare :Valérie Harang; Douglas Westerlund; Sven P. Jacobsson; Bo Karlberg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; optimisation; separation; chemometrics; high performance liquid chromatography; electrodriven techniques; microemulsion electrokinetic chromatography; statistical experimental design; molecular modelling; chiral separation; cellobiohydrolase; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : Statistical experimental designs have been used for method development and optimisation of separation. Two reversed phase HPLC methods were optimised. LÄS MER

  5. 10. Supercritical fluid chromatography and two-dimensional liquid chromatography : From new applications to technical innovations

    Författare :Mingzhe Sun; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Lignin depolymerisation can be utilized to produce value-added aromatic compounds. One of the major challenges in lignin depolymerisation study is the development of effective analytical tools to unravel the huge complexity of the depolymerisation product mixture. LÄS MER