Sökning: "HiRIEF LC-MS"

Hittade 3 avhandlingar innehållade orden HiRIEF LC-MS.

  1. 1. Multi-omics analysis of relapsed acute myeloid leukemia

    Författare :Svea Stratmann; Linda Holmfeldt; Caroline Heckman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute myeloid leukemia AML ; relapse and resistance; next generation sequencing WGS WES ; RNA-sequencing; DNA methylation; HiRIEF LC-MS; proteogenomics; Molekylär medicin; Molecular Medicine;

    Sammanfattning : The prognosis for patients suffering from acute myeloid leukemia (AML) remains unsatisfactory and survival is often measured in months. Although the majority of patients achieve complete remission after aggressive treatment, most of them relapse within a few years. LÄS MER

  3. 2. Discovering circulating protein biomarkers through in-depth plasma proteomics

    Författare :Haris Babačić; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Plasma, i.e., the liquid component of blood, is one of the most clinically used samples for biomarker measurement. LÄS MER

  4. 3. Molecular aspects of tumor development and treatment for small intestinal neuroendocrine tumors

    Författare :Omid Fotouhi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Small intestinal neuroendocrine tumors (SI-NETs) may cause symptoms due to excess secretion of hormones and peptides. The molecular mechanisms behind development of SINETs are not well understood. Copy number alterations, especially loss of chromosome 18q, have been reported and recently p27 mutations were implicated in SI-NET tumorigenesis. LÄS MER