Sökning: "Hepatitis C virus RNA"

Visar resultat 1 - 5 av 30 avhandlingar innehållade orden Hepatitis C virus RNA.

  1. 1. Hepatitis C virus. Aspects on natural history, antibody response, and viral quantification

    Författare :Martin Lagging; Göteborgs universitet; []
    Nyckelord :Hepatitis C virus; nosocomial infection; pseudotyped virus; fibrosis; viral quantification;

    Sammanfattning : Hepatitis C virus (HCV) is the major cause of parenterally transmitted non-A, non-B hepatitis, and is associated with chronic hepatitis, cirrhosis, and hepatocellular carcinoma. Despite the screening of blood products nosocomial spread of HCV continues to occur. LÄS MER

  3. 2. Hepatitis C virus kinetics during antiviral treatment

    Författare :Tony Carlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Hepatitis C virus RNA; genotype; kinetics; interferon-alpha; ribavirin.;

    Sammanfattning : It is estimated that 170 million individuals have chronic hepatitis C virus (HCV) infection, whereof 20-30% will develop end stage liver disease within 20-30 years. Antiviral therapy can stop this deterioration and clear the infection in 40-80% of the patients depending on treatment and HCV genotype. LÄS MER

  4. 3. Immunoglobulins, immunoglobulin subclass-distributions and serologic markers in some renal and systemic disorders

    Författare :Gabriel Almroth; Jan Björklander; Linköpings universitet; []
    Nyckelord :Immunoglobulins; immunoglobulin-subclass distribution; hydralazine; ANCA; anti-:MPO; primary SjOgren s syndrome; hepatitis B vaccination; anti-HBssubclasses; immunoadsorption; plasmapheresis; antibodies; hepatitis C virus; transmission; recombinant immunoblot assay; hepatitis C genotype; MEDICINE; MEDICIN;

    Sammanfattning : In this study we evaluated pathogenetic factors and possible mediators of renal and systemic disorders where immunologic mechanisms might be of importance.An abberant immunoglobulin and IgG-subclass distribution was detected in 103 patients with primary and secondary glomerulonephritis as well as in 38 patients with the systemic disease primary Sjögren 's syndrome or purpura hypergammaglobulinemica (elevated IgG1 and low IgG2 ). LÄS MER

  5. 4. On the outcome of antiviral therapy for hepatitis C virus genotype 2 or 3 infection

    Författare :Åsa Alsiö; Göteborgs universitet; []
    Nyckelord :infectious diseases; virology; hepatitis c; treatment;

    Sammanfattning : Abstract Approximately 80% of patients infected with HCV genotypes 2 or 3 achieve a sustained virological response (SVR), following 24 weeks of therapy with ribavirin and pegylated interferon (peg-IFN), but in light of considerable side effects and cost, shortened treatment duration without impaired efficacy is desirable. Thus, 382 genotype 2/3 infected patients were randomized in an investigator-initiated phase III study (NORDynamIC) evaluating the efficacy of 12 (short-term) vs. LÄS MER

  7. 5. Epidemiology and clinical importance of GB virus C/hepatitis G virus

    Författare :Robert Halasz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :GBV-C; HGV; prevalence; transmission; children; fulminant hepatic failure; clinical importance;

    Sammanfattning : GB virus C (GBV-C) or hepatitis G virus (HGV) is a recently discovered enveloped RNA virus belonging to the Flaviviridae family. GBV-C/HGV has been suggested to be a causative agent of non-A-non-E hepatitis. However, several contradictory observations cast doubts that it actually causes hepatitis. LÄS MER